Multicentre cross-sectional clinical evaluation study about quality of life in adults with disorders/differences of sex development (DSD) compared to country specific reference populations (dsd-LIFE)

Table 4 WHOQOL-BREF per domain and diagnosis for those included into the regression analyses

WHOQOL-BREF domain	Turner Syndrome			Klinefelter Syndrome			CAH			XY-DSD female			XY-DSD male			p
Domain	n	Mean	SD	n	Mean	SD	n	Mean	SD	n	Mean	SD	n	Mean	SD
	301	Mean	SD	213	Mean	SD	221	Mean	SD	194	Mean	SD	93	Mean	SD
Physical health
Range 0–100	283	71.5	16.8	200	66.4	19.4	211	68.1	18.9	187	73.9	17.9	86	73.1	18.1	< 0.001
Range 4–20		15.4	2.7		14.6	3.1		14.9	3.0		15.8	2.9		15.7	2.9
Psychological
Range 0–100	284	63.7	16.1	201	63.3	17.8	211	65.6	18.4	188	64.6	18.9	87	63.2	20.2	0.663
Range 4–20		14.2	2.6		14.1	2.8		14.5	2.9		14.3	3.0		14.1	3.2
Social relationships
Range 0–100	283	65.9	18.6	201	59.4	21.9	211	64.8	20.5	188	62.6	20.7	87	57.2	23.4	< 0.001
Range 4–20		14.5	3.0		13.5	3.5		14.4	3.3		14.0	3.3		13.2	3.7
Environment
Range 0–100	283	73.9	12.9	201	69.9	14.9	211	74.1	15.7	187	75.0	15.4	87	72.2	13.8	0.005
Range 4–20		15.8	2.1		15.2	2.4		15.9	2.5		16.0	2.5		15.6	2.2

(The values of the WHOQOL-BREF are shown with range 0–100 as well as range 4–20) (n = 1022)

ISSN: 1477-7525