The German version of the Expanded Prostate Cancer Index Composite (EPIC): translation, validation and minimal important difference estimation

Table 4 Correlation coefficients^a for the EPIC domain summary scores with validation instruments between change scores from baseline to follow-up (n = 92^b)

	Change from baseline to follow-up
	EPIC domain summary scores
	Urinary (95% CI)	Bowel (95% CI)	Sexual (95% CI)	Hormonal (95% CI)
EORTC PR-25
Urinary symptoms	−0.69 (− 0.79, − 0.56)
Bowel symptoms		−0.53 (− 0.67, − 0.35)
Hormonal treatment				−0.54 (− 0.68, − 0.36)
Sexual activity			0.58 (0.41, 0.71)
Sexual functioning			0.55 (0.24, 0.76)
Feeling Thermometer^b	0.27 (0.03, 0.48)	0.07 (−0.18, 0.21)	0.21 (−0.04, 0.43)	0.50 (0.29, 0.66)
SF-36
Physical Functioning	0.28 (0.08, 0.46)
Social Functioning		0.08 (−0.13, 0.28)
Bodily Pain		0.34 (0.14, 0.51)
Role Emotional	0.30 (0.10, 0.48)		0.20 (−0.01, 0.39)	0.45 (0.27, 0.60)
General Health				0.42 (0.23, 0.58)
Vitality				0.48 (0.30, 0.62)

Abbreviations: EPIC Expanded Prostate Cancer Index Composite, EORTC PR25 European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire–Prostate 25; Hormonal treatment = Hormonal treatment-related symptoms. CI=Confidence Interval
^aCorrelation coefficients according to distribution: Pearson correlations coefficients for normally distributed change scores. Correlation coefficients are boldface font when they met our assumptions and normal font when they were higher or lower than expected
^bMissing values: Correlations between EPIC and EORTC PR-25 domains: 3 to 13, except for EPIC sexual and EORTC PR25 sexual functioning domains (=62); Correlations between EPIC domains and Feeling Thermometer: change = 27–28; Correlations between EPIC and SF-36 domains: all time points = 0–2

ISSN: 1477-7525