Skip to main content

Table 1 Characteristics and outcome of patients treated with brachytherapy

From: Quality of life after low-dose rate-brachytherapy for prostate carcinoma – long-term results and literature review on QLQ-C30 and QLQ-PR25 results in published brachytherapy series

Characteristics   Initial Cohort n = 296 (100%)
Gleason Score ≤ 6 173 (58.4%)
>  6 32 (10.8%)
Unknown 91 (30.7%)
Preoperative PSA value ≤ 10 ng/ml 208 (70.3%)
>  10 (−20) ng/ml 62 (20.9%)
>  20 ng/ml 26 (8.8%)
Risk groupa Low 110 (37.1%)
Intermediate 26 (8.8%)
High 52 (17.6%)
Unknown 90 (30.4%)
T3 (n = 15), N1 (n = 2), or M1 (n = 1) 18 (6.1%)
Endpoint Clinical outcome Number of Patients (Percentage)
  All patients 296 (100%)
Overall survival in all
(n = 296) patients
Died before 2004 (Original cohort)
Died between 2004 and 2013 (Current cohort)
38 (12.8%)
32 (10.8%)
  Unknown
Alive but not willing to participate
Alive and contacted by phone
No available contact information but alive; clinical information as reported by urologist or general practitioner
100 (33.8%)
6 (2%)
114 (38.5%)
6 (2%)
  All deaths 70 (100%)
Causes of death in 70 patients who had died. Prostate carcinoma
Unrelated cancer
Leukemia
Gastric cancer
Pancreatic cancer
Lung cancer
Cardiovascularb
Infectionc
Kidney failure
Other or unknown
20 (28.6%)
8 (11.4%)
2
1
3
2
16 (22.9%)
3 (4.3%)
3 (4.3%)
20 (28.6%)
  Patients contacted 120 (100%)
Biochemical recurrence at any time in n = 120 patients with clinical information who were alive at final follow-up Biochemical recurrence present at any time 22 (18.3%)
No biochemical recurrence 68 (56.7%)
Unknown biochemical outcome 30 (25%)
  All patients with biochemical recurrence 22 (100%)
Clinical recurrence in patients who are alive and had biochemical recurrence Local recurrence at any time
Distant metastases at any time
Distant and local recurrence
Unknown
10 (45.4%)
2 (9.1%)
1 (4.5%)
13 (59.1%)
  1. aPatients with unknown Gleason Score were classified as high risk, if any high risk criteria were met (e.g. patients with PSA > 20 ng/ml were considered as high risk, even in case of unknown Gleason Score)
  2. bCardiovascular includes: Myocardial infarction, stroke, cerebral hemorrhage in a Marcumar patient, ruptured aortic aneurism, and cardiac arrest in coronary heart disease
  3. cInfection includes pneumonia and sepsis