Table 4 Known-Groups Validity of Duration of MJS and Severity of MJS Using DAS28-ESR Subgroups at Day 1 and Week 4, and CDAI Subgroups at Day 1

PRO/Study

p-value, ES

≤5.1

N, Mean (SD), Median

>5.1

N, Mean (SD), Median

 RA-BEAM

39, 120.5 (190.8), 60.0

496, 155.3 (180.1), 90.0

0.028^a, 0.19

 RA-BUILD

36, 132.8 (191.5), 60.0

273, 164.9 (173.1), 120

0.033^a, 0.18

 RA-BEAM

619, 76.1 (108.6), 37.3

587, 133.6 (153.5), 73.6

0.001^a, 0.43

 RA-BUILD

327, 77.6 (112.0), 40.0

286, 151.1 (158.3), 94.6

0.001^a, 0.54

 RA-BEAM

39, 4.4 (2.7)

496, 5.9 (2.1)

0.001^b, 0.70

 RA-BUILD

36, 4.0, (1.7)

274, 5.9 (2.0)

0.001^b, 0.97

 RA-BEAM

619, 3.0 (1.9)

587, 5.1 (2.1)

0.001^b, 1.05

 RA-BUILD

327, 3.1 (1.9)

286, 5.3 (2.0)

0.001^b, 1.13

p-value, ES

0.0 to ≤22.0

N, Mean (SD), Median

>22.0 to ≤76.0

N, Mean (SD), Median

 RA-BEAM

36, 144.1 (198.3), 90.0

497, 153.9 (180.0), 90.0

0.305^a, 0.05

 RA-BUILD

26, 111.9 (162.7), 60.0

278, 162.3 (170.6), 120

0.016^a, 0.30

 RA-BEAM

36, 4.7 (2.4)

497, 5.9 (2.1)

0.001^b, 0.57

 RA-BUILD

26, 3.7 (1.6)

278, 5.9 (2.1)

0.001^b, 1.07