Instruments | Duration of MJS | Severity of MJS | ||||||
---|---|---|---|---|---|---|---|---|
RA-BEAM | RA-BUILD | RA-BEAM | RA-BUILD | |||||
Number | r | Number | r | Number | r | Number | r | |
Day 1 | ||||||||
 Duration of MJS | – | – | – | – | 537 | 0.36*** | 311 | 0.35*** |
 Severity of MJS | 537 | 0.36*** | 311 | 0.35*** | – | – | – | – |
 Severity of Worst Tiredness | 537 | 0.21*** | 311 | 0.09 | 537 | 0.66*** | 311 | 0.52*** |
 Severity of Worst Joint Pain | 537 | 0.29*** | 310 | 0.30*** | 537 | 0.79*** | 310 | 0.75*** |
 SF-36 | ||||||||
  Role Physical Domain | 535 | −0.24*** | 311 | −0.23*** | 535 | −0.43*** | 312 | −0.40*** |
  Bodily Pain Domain | 535 | −0.30*** | 311 | −0.29*** | 535 | −0.65*** | 312 | −0.51*** |
  General Health Domain | 535 | −0.09* | 311 | −0.18** | 535 | −0.30*** | 312 | −0.25*** |
  Social Functioning Domain | 535 | −0.16*** | 311 | −0.24*** | 535 | −0.38*** | 312 | −0.41*** |
  Vitality Domain | 535 | −0.21*** | 311 | −0.18** | 535 | −0.42*** | 312 | −0.32*** |
  Role Emotional Domain | 535 | −0.07 | 311 | −0.12* | 535 | −0.27*** | 312 | −0.25*** |
  Mental Health Domain | 535 | −0.10* | 311 | −0.20*** | 535 | −0.31*** | 312 | −0.27*** |
  Physical Functioning Domain | 535 | −0.25*** | 311 | −0.28*** | 535 | −0.51*** | 312 | −0.47*** |
  Mental Component Score | 535 | −0.07 | 311 | −0.15** | 535 | −0.26*** | 312 | −0.25*** |
  Physical Component Score | 535 | −0.29*** | 311 | −0.27*** | 535 | −0.54*** | 312 | −0.44*** |
 HAQ-DI Total Score | 535 | 0.22*** | 311 | 0.26*** | 535 | 0.53*** | 312 | 0.46*** |
 QIDS-SR16 Total Score | 535 | 0.15*** | 311 | 0.26*** | 535 | 0.34*** | 312 | 0.28*** |
 Patient’s Assessment of Pain | 535 | 0.24*** | 311 | 0.23*** | 535 | 0.59*** | 312 | 0.54*** |
 PtGA | 535 | 0.19*** | 311 | 0.28*** | 535 | 0.59*** | 312 | 0.53*** |
 Tender Joint Count 28 | 537 | 0.09* | 311 | 0.15** | 537 | 0.26*** | 312 | 0.43*** |
 Swollen Joint Count 28 | 537 | 0.06 | 311 | 0.13* | 537 | 0.21*** | 312 | 0.24*** |
 PhGA | 535 | 0.19*** | 304 | 0.19*** | 535 | 0.32*** | 305 | 0.33*** |
 hsCRP | 535 | 0.20*** | 311 | 0.27*** | 535 | 0.48*** | 312 | 0.53*** |
Week 12a | ||||||||
 Duration of MJS | – | – | – | – | 1281 | 0.45*** | 666 | 0.52*** |
 Severity of MJS | 1281 | 0.45*** | 666 | 0.52*** | – | – | – | – |
 Severity of Worst Tiredness | 1281 | 0.32*** | 666 | 0.38*** | 1281 | 0.79*** | 666 | 0.77*** |
 Severity of Worst Joint Pain | 1281 | 0.41*** | 666 | 0.47*** | 1281 | 0.89*** | 666 | 0.89*** |
 SF-36 | ||||||||
  Role Physical Domain | 1233 | −0.23*** | 632 | −0.29*** | 1233 | −0.47*** | 632 | −0.45*** |
  Bodily Pain Domain | 1233 | −0.31*** | 632 | −0.36*** | 1233 | −0.59*** | 632 | −0.55*** |
  General Health Domain | 1233 | −0.15*** | 632 | −0.19*** | 1233 | −0.36*** | 632 | −0.30*** |
  Social Functioning Domain | 1233 | −0.18*** | 632 | −0.30*** | 1233 | −0.43*** | 632 | −0.46*** |
  Vitality Domain | 1233 | −0.19*** | 632 | −0.29*** | 1233 | −0.41*** | 632 | −0.39*** |
  Role Emotional Domain | 1233 | −0.18*** | 632 | −0.23*** | 1233 | −0.39*** | 632 | −0.33*** |
  Mental Health Domain | 1233 | −0.16*** | 632 | −0.21*** | 1233 | −0.33*** | 632 | −0.30*** |
  Physical Functioning Domain | 1233 | −0.22*** | 632 | −0.32*** | 1233 | −0.49*** | 632 | −0.46*** |
  Mental Component Score | 1233 | −0.14*** | 632 | −0.21*** | 1233 | −0.31*** | 632 | −0.29*** |
  Physical Component Score | 1233 | −0.25*** | 632 | −0.31*** | 1233 | −0.52*** | 632 | −0.48*** |
 HAQ-DI Total Score | 1233 | 0.23*** | 632 | 0.31*** | 1233 | 0.55*** | 632 | 0.51*** |
 QIDS-SR16 Total Score | 1231 | 0.20*** | 632 | 0.24*** | 1231 | 0.34*** | 632 | 0.31*** |
 Patient’s Assessment of Pain | 1233 | 0.38*** | 632 | 0.39*** | 1233 | 0.78*** | 632 | 0.72*** |
 PtGA | 1233 | 0.36*** | 632 | 0.37*** | 1233 | 0.74*** | 632 | 0.67*** |
 Tender Joint Count 28 | 1231 | 0.16*** | 630 | 0.31*** | 1231 | 0.39*** | 630 | 0.44*** |
 Swollen Joint Count 28 | 1231 | 0.16*** | 630 | 0.22*** | 1231 | 0.28*** | 630 | 0.31*** |
 PhGA | 1224 | 0.21*** | 627 | 0.29*** | 1224 | 0.41*** | 627 | 0.44*** |
 hsCRP | 1220 | 0.26*** | 623 | 0.37*** | 1220 | 0.57*** | 623 | 0.57*** |