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Table 3 Pearson Correlations between Duration of MJS, Severity of MJS, Severity of Worst Tiredness, and Other Instruments in RA-BEAM and RA-BUILD

From: Psychometric properties of morning joint stiffness duration and severity measures in patients with moderately to severely active rheumatoid arthritis

Instruments

Duration of MJS

Severity of MJS

RA-BEAM

RA-BUILD

RA-BEAM

RA-BUILD

Number

r

Number

r

Number

r

Number

r

Day 1

 Duration of MJS

–

–

–

–

537

0.36***

311

0.35***

 Severity of MJS

537

0.36***

311

0.35***

–

–

–

–

 Severity of Worst Tiredness

537

0.21***

311

0.09

537

0.66***

311

0.52***

 Severity of Worst Joint Pain

537

0.29***

310

0.30***

537

0.79***

310

0.75***

 SF-36

  Role Physical Domain

535

−0.24***

311

−0.23***

535

−0.43***

312

−0.40***

  Bodily Pain Domain

535

−0.30***

311

−0.29***

535

−0.65***

312

−0.51***

  General Health Domain

535

−0.09*

311

−0.18**

535

−0.30***

312

−0.25***

  Social Functioning Domain

535

−0.16***

311

−0.24***

535

−0.38***

312

−0.41***

  Vitality Domain

535

−0.21***

311

−0.18**

535

−0.42***

312

−0.32***

  Role Emotional Domain

535

−0.07

311

−0.12*

535

−0.27***

312

−0.25***

  Mental Health Domain

535

−0.10*

311

−0.20***

535

−0.31***

312

−0.27***

  Physical Functioning Domain

535

−0.25***

311

−0.28***

535

−0.51***

312

−0.47***

  Mental Component Score

535

−0.07

311

−0.15**

535

−0.26***

312

−0.25***

  Physical Component Score

535

−0.29***

311

−0.27***

535

−0.54***

312

−0.44***

 HAQ-DI Total Score

535

0.22***

311

0.26***

535

0.53***

312

0.46***

 QIDS-SR16 Total Score

535

0.15***

311

0.26***

535

0.34***

312

0.28***

 Patient’s Assessment of Pain

535

0.24***

311

0.23***

535

0.59***

312

0.54***

 PtGA

535

0.19***

311

0.28***

535

0.59***

312

0.53***

 Tender Joint Count 28

537

0.09*

311

0.15**

537

0.26***

312

0.43***

 Swollen Joint Count 28

537

0.06

311

0.13*

537

0.21***

312

0.24***

 PhGA

535

0.19***

304

0.19***

535

0.32***

305

0.33***

 hsCRP

535

0.20***

311

0.27***

535

0.48***

312

0.53***

Week 12a

 Duration of MJS

–

–

–

–

1281

0.45***

666

0.52***

 Severity of MJS

1281

0.45***

666

0.52***

–

–

–

–

 Severity of Worst Tiredness

1281

0.32***

666

0.38***

1281

0.79***

666

0.77***

 Severity of Worst Joint Pain

1281

0.41***

666

0.47***

1281

0.89***

666

0.89***

 SF-36

  Role Physical Domain

1233

−0.23***

632

−0.29***

1233

−0.47***

632

−0.45***

  Bodily Pain Domain

1233

−0.31***

632

−0.36***

1233

−0.59***

632

−0.55***

  General Health Domain

1233

−0.15***

632

−0.19***

1233

−0.36***

632

−0.30***

  Social Functioning Domain

1233

−0.18***

632

−0.30***

1233

−0.43***

632

−0.46***

  Vitality Domain

1233

−0.19***

632

−0.29***

1233

−0.41***

632

−0.39***

  Role Emotional Domain

1233

−0.18***

632

−0.23***

1233

−0.39***

632

−0.33***

  Mental Health Domain

1233

−0.16***

632

−0.21***

1233

−0.33***

632

−0.30***

  Physical Functioning Domain

1233

−0.22***

632

−0.32***

1233

−0.49***

632

−0.46***

  Mental Component Score

1233

−0.14***

632

−0.21***

1233

−0.31***

632

−0.29***

  Physical Component Score

1233

−0.25***

632

−0.31***

1233

−0.52***

632

−0.48***

 HAQ-DI Total Score

1233

0.23***

632

0.31***

1233

0.55***

632

0.51***

 QIDS-SR16 Total Score

1231

0.20***

632

0.24***

1231

0.34***

632

0.31***

 Patient’s Assessment of Pain

1233

0.38***

632

0.39***

1233

0.78***

632

0.72***

 PtGA

1233

0.36***

632

0.37***

1233

0.74***

632

0.67***

 Tender Joint Count 28

1231

0.16***

630

0.31***

1231

0.39***

630

0.44***

 Swollen Joint Count 28

1231

0.16***

630

0.22***

1231

0.28***

630

0.31***

 PhGA

1224

0.21***

627

0.29***

1224

0.41***

627

0.44***

 hsCRP

1220

0.26***

623

0.37***

1220

0.57***

623

0.57***

  1. Abbreviations: HAQ-DI Health Assessment Questionnaire-Disability Index, hsCRP high-sensitivity C-reactive protein, MJS morning joint stiffness, n number of patients, PtGA Patient’s Global Assessment of Disease Activity, PhGA Physician’s Global Assessment of Disease Activity, QIDS-SR 16 Quick Inventory of Depressive Symptomatology Self-Rated-16, SF-36 36-Item Short Form Health Survey version 2 with Acute recall
  2. Pearson correlation coefficients with significance using p-values denoted as: * ≤ 0.05, ** ≤ 0.01, *** ≤ 0.001
  3. aDaily average of 7 days preceding visit that contained at least 4 measurements [29]