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Table 7 Known-Groups Validity of Severity of Worst Tiredness Using CDAI Subgroups at Week 4

From: Psychometric properties of the single-item measure, severity of worst tiredness, in patients with moderately to severely active rheumatoid arthritis

PRO/Study

CDAI Category

p-valuea

Comparisonsb

0.0 to ≤ 10.0

N, Mean (SD)

>10.0 to ≤ 22.0

N, Mean (SD)

>22.0 to ≤ 76.0

N, Mean (SD)

Severity of Worst Tiredness Week 4

     

 RA-BEAM

220, 2.9 (2.0)

426, 4.2 (2.1)

567, 5.1 (2.0)

0.001

a: 0.001, b: 0.001, c: 0.001

 RA-BUILD

134, 3.1 (2.0)

209, 4.1 (1.9)

275, 5.6 (2.0)

0.001

a: 0.001, b: 0.001, c: 0.001

  1. Abbreviations: SD = standard deviation; CDAI = Clinical Disease Activity Index
  2. ap-value based on a comparison of mean values using ANOVA
  3. bNote for multiple comparison using Scheffé adjustment: a: 0.0 to ≤10.0 versus >10.0 to ≤22.0; b: 0.0 to ≤10.0 versus >22.0 to ≤76.0; c: >10.0 to ≤22.0 versus >22.0 to ≤76.0