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Table 2 Instrument Scores at Day 1 and Week 12 for RA-BEAM and RA-BUILD

From: Psychometric properties of the single-item measure, severity of worst tiredness, in patients with moderately to severely active rheumatoid arthritis

Instrument

RA-BEAMa

RA-BUILDb

Day 1

Week 12

Day 1

Week 12

Severity of Worst Tiredness, Mean (SD)

5.8 (2.1)

4.0 (2.3)

6.0 (2.1)

4.1 (2.4)

Duration of MJS, Mean (SD)

152.8 (180.8)

96.7 (144.7)

160.7 (174.8)

103.5 (147.5)

Severity of MJS, Mean (SD)

5.8 (2.2)

3.5 (2.4)

5.7 (2.1)

3.7 (2.4)

Severity of Worst Joint Pain, Mean (SD)

6.1 (2.0)

4.0 (2.3)

6.0 (2.1)

4.2 (2.4)

Patient’s Assessment of Pain, Mean (SD)

60.8 (22.3)

34.9 (24.1)

58.0 (22.1)

36.5 (24.9)

PtGA, Mean (SD)

62.4 (21.8)

36.3 (23.5)

60.7 (21.1)

37.7 (24.0)

SF-36

    

 Role Physical Domain, Mean (SD)

35.5 (10.4)

41.8 (10.2)

35.3 (9.2)

40.7 (9.6)

 Bodily Pain Domain, Mean (SD)

34.7 (7.8)

42.5 (8.7)

34.9 (7.6)

41.9 (9.0)

 General Health Domain, Mean (SD)

36.8 (8.5)

41.6 (8.9)

36.8 (8.3)

42.0 (9.4)

 Social Functioning Domain, Mean (SD)

40.8 (11.6)

45.4 (10.5)

40.2 (11.2)

44.7 (10.3)

 Vitality Domain, Mean (SD)

43.7 (10.0)

49.4 (9.8)

41.9 (10.1)

48.4 (10.0)

 Role Emotional Domain, Mean (SD)

41.1 (12.6)

45.5 (10.9)

40.9 (12.3)

44.8 (11.2)

 Mental Health Domain, Mean (SD)

43.0 (11.3)

47.1 (10.7)

42.9 (11.6)

47.1 (11.3)

 Physical Functioning Domain, Mean (SD)

32.2 (10.4)

38.7 (10.9)

32.2 (10.2)

38.2 (10.9)

 Mental Component Score, Mean (SD)

46.4 (11.8)

49.8 (10.8)

45.7 (11.8)

49.3 (11.1)

 Physical Component Score, Mean (SD)

32.3 (8.6)

39.4 (9.3)

32.3 (8.3)

38.8 (9.4)

FACIT-F Total Score, Mean (SD)

28.2 (10.9)

36.8 (9.6)

26.8 (11.2)

35.5 (10.1)

QIDS-SR16 Total Score, Mean (SD)

8.0 (5.0)

5.9 (4.2)

8.4 (4.9)

6.2 (4.3)

HAQ-DI Total Score, Mean (SD)

1.56 (0.68)

1.03 (0.70)

1.52 (0.61)

1.03 (0.66)

PhGA, Mean (SD)

65.0 (16.9)

31.0 (21.7)

63.5 (17.4)

33.9 (22.4)

CDAI, Mean (SD)

37.83 (12.55)

18.68 (13.54)

36.05 (12.12)

18.04 (13.15)

DAS28-ESR, Mean (SD)

6.43 (0.97)

4.62 (1.46)

6.22 (0.97)

4.50 (1.37)

DAS28-hsCRP, Mean (SD)

5.73 (0.94)

3.93 (1.39)

5.55 (0.91)

3.84 (1.35)

  1. Abbreviations: CDAI = Clinical Disease Activity Index; DAS28 = Disease Activity Score modified to include the 28 diarthrodial joint count; ESR = erythrocyte sedimentation rate; FACIT-F = Functional Assessment of Chronic Illness Therapy-Fatigue; HAQ-DI = Health Assessment Questionnaire-Disability Index; hsCRP = high-sensitivity C-reactive protein; n = number of patients; MJS = morning joint stiffness; PhGA = Physician’s Global Assessment of Disease Activity; PtGA = Patient’s Global Assessment of Disease Activity; QIDS-SR16 = Quick Inventory of Depressive Symptomatology Self-Rated-16; SD = standard deviation; SF-36 = 36-Item Short Form Health Survey version 2 with Acute recall
  2. aDaily diary responses were n = 537(Day 1) and n = 1281 (Week 12); nondiary assessments had approximately n = 1301 (Day 1) and n = 1250 (Week 12)
  3. bDaily diary responses were n = 310 (Day 1) and n = 666 (Week 12); nondiary assessments had approximately n = 680 (Day 1) and n = 644 (Week 12)
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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