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Table 3 Association between clusters intra-groups of metabolic, cardiovascular, cardiovascular, and musculoskeletal conditions with the health related quality of life among individuals ≥20 years in South Australia, 2015 (N = 2912)

From: Individual diseases or clustering of health conditions? Association between multiple chronic diseases and health-related quality of life in adults

  

Physical component score

 

Mental component score

 

(%)

Crude

Adjusted

Crude

Adjusted

   

Model 1

Model 2

 

Model 1

Model 2

  

Mean (SE)

Mean (SE)

Mean (SE)

Mean (SE)

Mean (SE)

Mean (SE)

Metabolic conditions

 

p < 0.001

p < 0.001

p < 0.001

p = 0.21

p = 0.99

p = 0.90

None

61.4

51.1 (0.3)

49.9 (0.2)

49.4 (0.2)

52.5 (0.2)

52.4 (0.2)

52.4 (0.2)

1

27.9

45.3 (0.4)

46.5 (0.4)

47.1 (0.3)

52.4 (0.4)

52.5 (0.3)

52.4 (0.3)

2+

10.7

40.8 (0.7)

44.7 (0.6)

46.3 (0.6)

51.7 (0.5)

52.4 (0.4)

52.3 (0.4)

R 2

 

12.4%

30.2%

36.9%

0.1%

23.4%

24.1%

Cardiovascular conditions

 

p < 0.001

p < 0.001

p < 0.001

p = 0.02

p = 0.51

p = 0.39

None

74.0

50.5 (0.2)

49.4 (0.2)

49.0 (0.2)

52.1 (0.2)

52.3 (0.2)

52.3 (0.2)

1

19.1

44.1 (0.6)

46.8 (0.6)

47.8 (0.5)

53.3 (0.7)

53.1 (0.3)

53.1 (0.4)

2+

6.9

37.9 (0.8)

42.4 (0.9)

44.3 (0.9)

52.8 (1.1)

52.1 (0.6)

52.3 (0.6)

R 2

 

13.2%

29.5%

36.9%

0.3%

23.5%

24.1%

Gastrointestinal conditions

 

p < 0.001

p < 0.001

p < 0.001

p < 0.001

p < 0.001

p = 0.001

None

83.6

49.2 (0.3)

48.9 (0.2)

48.7 (0.2)

52.8 (0.2)

52.7 (0.2)

52.7 (0.2)

1

14.3

44.7 (0.6)

46.2 (0.5)

46.7 (0.5)

50.7 (0.5)

51.6 (0.5)

51.6 (0.5)

2+

2.1

44.7 (1.6)

43.2 (1.3)

45.0 (1.3)

47.1 (1.5)

48.7 (1.1)

49.2 (1.1)

R 2

 

3.8%

28.4%

36.9%

1.5%

23.9%

24.1%

Musculoskeletal conditions

 

p < 0.001

p < 0.001

p < 0.001

p = 0.18

p = 0.16

p = 0.34

None

69.5

51.4 (0.2)

50.5 (0.2)

50.2 (0.2)

52.6 (0.2)

52.5 (0.2)

52.5 (0.2)

1

24.4

42.1 (0.4)

44.0 (0.4)

44.6 (0.4)

52.1 (0.5)

52.4 (0.4)

52.5 (0.4)

2+

6.1

38.9 (0.8)

42.1 (0.8)

43.2 (0.7)

51.7 (0.8)

51.2 (0.7)

51.4 (0.7)

R 2

 

20.1%

33.6%

36.9%

0.1%

23.5%

24.1%

  1. Metabolic conditions: obesity, dyslipidaemia, and/or diabetes mellitus. Cardiovascular conditions: hypertension, myocardial infarction, angina, atrial fibrillation, heart failure, and/or stroke. Gastrointestinal conditions: irritable bowel syndrome, gastroesophageal reflux, coeliac disease, Chrohn’s disease and/or ulcerative colitis. Musculoskeletal conditions: osteoarthritis, gout and/or osteoporosis
  2. Model 1: predicted means adjusted for sex, age, marital status, area of residence, educational level, working status, socioeconomic position (Socio-Economic Indexes for Areas Index of Relative Socio-economic Advantage and Disadvantaged), fruit/vegetable consumption, physical activity, smoking status, alcohol intake, and mental health status
  3. Model 2: predicted means adjusted for variables in model 1 + mutual adjustment between the cluster intragroup of chronic conditions
  4. R2 = Determination coefficient in %. Adjusted R2 for models including just sociodemographic, lifestyle, and mental health status variables were 27.2% for PCS and 23.4% for MCS. The R2 for Model 2 is the same for all clusters intragroup, as the regression models included a mutual adjustment between them