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Table 2 Peds QoL Generic and Fatigue Scores: In relation to norms

From: Health-related quality of life in children with congenital adrenal hyperplasia

QoL Score, Mean Children with CAH Healthy Children Mean difference (95% CI) Parents, CAH Children Parents, Healthy Children Mean difference (95% CI)
Generic QoL Scores (Overall and subscales)
 Overall 82.71 (n = 32) 83.00 (n = 401) −0.29 (−.25, 5.67) 83.90 (n = 43) 87.61 (n = 717) −3.71 (−7.37, −0.05)a
 Physical 90.53 (n = 32) 84.41 (n = 400) 6.12 (2.10, 10.14)a 89.10 (n = 44) 89.32 (n = 717) −0.22 (−3.52, 3.08)
 Emotional 80.16 (n = 32) 80.86 (n = 400) −0.70 (−6.96, 5.55) 75.90 (n = 44) 82.64 (n = 717) −6.74 (−12.36, −1.12)a
 Social 85.16 (n = 32) 87.42 (n = 399) −2.26 (−10.11, 5.58) 90.60 (n = 43) 91.56 (n = 716) −0.96 (−4.57, 2.65)
 School 75.00 (n = 32) 78.63 (n = 386) −3.63 (−9.78, 2.52) 78.99 (n = 40) 85.47 (n = 611) −6.48 (−12.75, −0.21)a
Fatigue Scores (Overall and subscales)
 Overall 79.08 (n = 32) 80.49 (n = 52) −1.41 (−7.85, 5.02) 81.90 (n = 42) 89.63 (n = 102) −7.73 (−12.24, −3.22)a
 General 82.81 (n = 32) 85.34 (n = 52) −2.53 (−9.13, 4.07) 82.40 (n = 42) 89.30 (n = 102) −6.90 (−12.34, −1.46)a
 Sleep/Rest 74.48 (n = 32) 75.00 (n = 52) −0.52 (−8.30, 7.25) 81.60 (n = 42) 88.86 (n = 102) −7.26 (−12.14, −2.38)a
 Cognitive 79.97 (n = 31) 81.14 (n = 52) −1.17 (−10.71, 8.37) 81.60 (n = 42) 90.72 (n = 102) −9.12 (−15.72, −2.52)a
  1. aIndicates a significant finding at the 0.05 significance level
  2. CAH congenital adrenal hyperplasia, QoL quality of life