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Table 2 Quality of life summary scores, arterial pressure indices and walking capacity at baseline and follow-up

From: Validation of the Vascular quality of life questionnaire – 6 for clinical use in patients with lower limb peripheral arterial disease

  All participants (n = 171) Conservative treatment (n = 68) Invasive treatment (n = 73) No follow-up (n = 30)
Baseline Baseline Follow-up Baseline Follow-up Baseline
  Mean (95% CI) Mean (95% CI) Mean (95% CI) p Mean (95% CI) Mean (95% CI) p Mean (95% CI)
VQ-6 sum 12.7 (12.2–13.3) 13.6 (12.8–14.4) 15.2 (14.3–16.1) 0.001 b 12.1 (11.4–12.8) 19.6 (15.8–18.0) 0.001 b 12.4 (10.7–14.0)
SF-36 PCS 33 (32–34) 35 (33–36) 38 (36–40) 0.001 b 32 (30–33) 40 (37–42) 0.001 b 32 (30–35)
SF-36 MCS 48 (47–50) 51 (48–53) 48 (45–51) 0.470 b 48 (45–51) 48 (46–51) 0.780 b 45 (40–50)
ABIa 0.62 (0.59–0.65) 0.65 (0.62–0.69) 0.67 (0.63–0.71) 0.394 b 0.57 (0.52–0.62) 0.76 (0.71–0.82) 0.001 b 0.64 (0.57–0.72)
ABI pea 0.47 (0.43–0.51) 0.55 (0.50–0.60) 0.53 (0.47–0.59) 0.597 b 0.36 (0.29–0.43) 0.67 (0.60–0.75) 0.001 b 0.54 (0.42–0.67)
  Median (IQ) Median (IQ) Median (IQ)   Median (IQ) Median (IQ)   Median (IQ)
ICD 87 (46–133) 100 (55–159) 107 (10–600) 0.036 c 62 (40–100) 110 (0–295) 0.001 c 110 (53–145)
MWD 400 (164–410) 410 (260–418) 410 (30–650) 0.066 c 233 (110–400) 403 (30–570) 0.001 c 410 (240–420)
  1. VQ-6 –Vascular Quality of Life Questionnarie-6, SF-36 –Short Form-36, PCS –Physical component summary score, MCS –Mental component summary score, ABI -ankle-brachial index, pe –postexercise, ICD –intermittent claudication distance, MWD –maximum walking distance, IQ –interquartile range (25th–75th percentile)
  2. aSymptomatic leg
  3. bTwo-tailed t-test for normally distributed data, p < 0.05 was regarded significant
  4. cWilcoxon signed rank test for non-normally distributed data, p < 0.05 was regarded significant