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Table 2 PROMIS II HRQOL domain scores at each assessment

From: Responsiveness of the PROMIS® measures to changes in disease status among pediatric nephrotic syndrome patients: a Midwest pediatric nephrology consortium study

 

Baseline

Event visit

Month 12

   

N = 127

N = 112

N = 90

PROMIS

Mean(SD)

Clinically impaired N(%)*

Mean(SD)

Clinically impaired N(%)*

Mean(SD)

Clinically impaired N(%)*

F-value

p-value

η2

Mobility

46.3 (9.2)

31 (25)

50.8 (9.5)

14 (13)

52.4 (9.2)

9 (10)

12.81

<0.001

0.074

Fatigue

49.6 (12.6)

29 (23)

43.4 (12.7)

9 (8)

43.3 (13.4)

11 (12)

9.16

<0.001

0.054

Pain Interference

49.7 (11.1)

24 (20)

44.9 (11.2)

7 (6)

44.7 (10.9)

10 (11)

7.44

<0.001

0.045

Depression

49.7 (9.3)

22 (18)

45.2 (9.9)

8 (7)

46.2 (9.6)

6 (7)

7.04

0.001

0.042

Anxiety

49.4 (10.6)

23 (19)

43.2 (11.5)

11 (10)

44.5 (10.7)

7 (8)

10.64

<0.001

0.062

Peer Relationships

48.6 (10.6)

23 (19)

50.4 (11.3)

16 (15)

51.7 (10.4)

7 (8)

2.15

0.12

0.013

PedsQL

         

Physical functioning

69.3 (22.7)

59 (47)

79.1 (20.8)

29 (27)

81.5 (21.1)

25 (28)

10.04

<0.001

0.059

Emotional functioning

72.3 (22.1)

61 (48)

80.1 (20.9)

33 (30)

80.5 (20.9)

27 (30)

5.42

0.005

0.032

Social functioning

80.6 (18.0)

25 (20)

84.0 (18.2)

18 (17)

85.2 (18.5)

16 (18)

1.91

0.15

0.012

School functioning

63.7 (21.2)

38 (35)

76.9 (20.3)

15 (16)

74.7 (21.1)

20 (25)

11.57

<0.001

0.076

Overall

71.0 (17.0)

44 (35)

80.0 (17.1)

21 (19)

80.5 (18.2)

20 (22)

10.91

<0.001

0.064

  1. *>1SD from the mean in the clinically impaired direction. For PROMIS Mobility, and Peer Relationships, a higher score indicates better patient reported outcomes; for PROMIS Fatigue, Pain Interference, Depression, and Anxiety a higher score indicates worse patient reported outcomes. For all PedsQL domains, a higher score indicates better patient reported outcomes
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