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Table 1 Study dataset summary and key baseline patient characteristics

From: Development of a new Rasch-based scoring algorithm for the National Eye Institute Visual Functioning Questionnaire to improve its interpretability

Indication

Trial

n (%)

Age (years) mean (SD, range)

BCVA letter score at baseline mean (SD, range), Snellen equivalents

DME

RESTORE [5]

344 (13.8)

64 (9, 37–87)

73 (11, 20/32)

96–40 (20/12–20/160)

Macular edema due to branch RVO

BRAVO [28]

392 (15.8)

66 (12, 26–91)

82 (11, 20/25)

99–29 (20/10–20/250)

Macular edema due to central RVO

CRUISE [27]

385 (15.5)

68 (13, 20–91)

81 (11, 20/25)

100–29 (20/10–20/250)

Neovascular AMD

ANCHOR [25]

418 (16.8)

77 (8, 53–96)

68 (18, 20/40)

100–2 (20/10–20/1000)

Neovascular AMD

MARINA [26]

716 (28.8)

77 (7, 52–95)

68 (15, 20/40)

99–19 (20/10–20/400)

CNV secondary to PM

RADIANCE [8]

232 (9.3)

56 (14, 18–87)

73 (13, 20/32)

95–30 (20/12–20/250)

Overall population

 

2487 (100)

64 (9, 18–96)

73 (15, 20/32)

100–2 (20/10–20/1000)

  1. AMD age-related macular degeneration, BCVA best-corrected visual acuity, BSE better-seeing eye, CNV choroidal neovascularization, DME diabetic macular edema, PM pathologic myopia, RVO retinal vein occlusion, SD standard deviation, VEGF vascular endothelial growth factor