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Table 4 Participants’ perceptions of sickle cell disease and hydroxyurea in relation to self-report adherence levels (N = 34)

From: Adherence to hydroxyurea, health-related quality of life domains, and patients’ perceptions of sickle cell disease and hydroxyurea: a cross-sectional study in adolescents and young adults

B-IPQ domains

©MMAS-8

©MMAS-8, median (IQR)

rs correlations

P-value

Low (n = 25)

Mod/High (n = 9)

P-value

Consequences

−0.26

0.13

6 (2, 8)

4 (0, 5)

0.08

Personal control

0.31

0.07

5 (3, 7)

5 (5, 9)

0.26

Treatment control

0.44

<0.01

7 (5, 9)

10 (8, 10)

0.04

Identity (symptoms)

−0.3

0.08

6 (3, 8)

0 (0, 4)

0.03

Concerns

−0.04

0.8

6 (2, 8)

5 (4, 10)

0.94

Understanding

0.2

0.25

9 (7, 10)

10 (8, 10)

0.38

Emotional response

−0.44

0.01

7 (0, 10)

0 (0, 1)

<0.01

  1. Data are presented as spearman correlations for MMAS-8 adherence scores, and as medians and inter-quartile ranges for the low and moderate/high MMAS-8 adherence categories
  2. P-value <0.05 was statistically significant (highlighted in bold)
  3. B-IPQ brief illness perception questionnaire; IQR inter-quartile range; © MMAS-8 ©Modified Morisky Adherence Scale 8-items; r s spearman correlations
  4. Higher ©MMAS-8 scores indicate better or higher adherence level to hydroxyurea
  5. Higher B-IPQ scores indicated worse perceptions of sickle cell disease related consequences, identity or disease-related symptoms, concerns, and emotional response, but better perceptions of personal control, treatment control, and understanding of sickle cell disease
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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