Adherence to hydroxyurea, health-related quality of life domains, and patients’ perceptions of sickle cell disease and hydroxyurea: a cross-sectional study in adolescents and young adults

Table 3 Perceptions of sickle cell disease and hydroxyurea in relation to healthcare utilization (N = 34)

B-IPQ domains	ED visits in 1 year		Hospitalizations in 1 year, median (IQR)
B-IPQ domains	r_s correlations	P-value	None (n = 14)	1–3 (n = 11)	≥ 4 (n = 9)	P-value
Consequences	0.68	<0.001	1 (0, 4)	5 (2, 7)	8 (7, 9)	<0.001
Personal control	– 0.28	0.11	7 (5, 10)	4 (2, 10)	5 (3, 5)	0.20
Treatment control	– 0.46	<0.01	10 (7, 10)	9 (5, 10)	5 (3, 7)	0.01
Identity (symptoms)	0.68	<0.001	0 (0, 1)	5 (4, 6)	8 (6, 10)	<0.001
Concerns	0.3	0.08	3 (0, 8)	5 (4, 8)	8 (6, 9)	0.11
Understanding	0.005	0.98	10 (7, 10)	9 (7, 10)	10 (8, 10)	0.72
Emotional response	0.65	<0.001	0 (0, 1)	7 (0, 8)	10 (8, 10)	<0.001

Data are presented as spearman correlations for ED visits, and as medians and inter-quartile ranges for hospitalizations categories
P-value <0.05 was statistically significant (highlighted in bold)
B-IPQ brief illness perception questionnaire; ED emergency department; IQR inter-quartile range
Higher B-IPQ scores indicated worse perceptions of sickle cell disease related consequences, identity or disease-related symptoms, concerns, and emotional response, but better perceptions of personal control, treatment control, and understanding of sickle cell disease

ISSN: 1477-7525