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Table 2 Health-related quality of life (HRQOL) scores according to physical activity levels among breast cancer survivors with stage I to III breast cancer

From: The association between physical activity and health-related quality of life among breast cancer survivors

HRQOL Items

Physical Activity (MET-hours per week)

All

Tertile 1

Tertile 2

Tertile 3

P for trenda

EORTC QLQ-C30, LS means (95% CI)b

Global health status / QoL

206

45.25 (33.62, 60.90)

31.99 (23.14, 44.22)

40.10 (29.17, 55.12)

0.64

Functioning

 Physical Functioning

229

78.44 (70.20, 87.65)

81.12 (71.93, 91.48)

82.53 (73.21, 93.05)

0.41

 Role Functioning

230

75.68 (59.77, 95.82)

83.78 (64.68, 108.51)

90.10 (69.98, 116.01)

0.18

 Emotional Functioning

231

75.16 (62.37, 90.58)

72.87 (59.47, 89.31)

75.67 (61.95, 92.44)

0.89

 Cognitive Functioning

231

75.13 (63.80, 88.47)

72.40 (60.60, 86.51)

71.47 (59.98, 85.16)

0.59

 Social Functioning

231

56.74 (44.62, 72.15)

73.08 (56.25, 94.94)

72.96 (56.39, 94.39)

0.08

Symptom

 Fatigue

230

21.63 (16.07, 29.11)

21.00 (15.20, 29.02)

13.30 (9.64, 18.36)

0.001

 Nausea / Vomiting

231

2.56 (1.60, 4.09)

2.33 (1.40, 3.89)

2.54 (1.53, 4.20)

0.97

 Pain

230

12.45 (7.44, 20.83)

7.90 (4.51, 13.83)

6.25 (3.58, 10.93)

0.02

 Dyspnea

228

5.83 (3.38, 10.03)

3.23 (1.79, 5.85)

4.07 (2.25, 7.37)

0.35

 Insomnia

229

12.60 (7.38, 21.53)

15.79 (8.81, 28.29)

16.22 (9.07, 29.00)

0.42

 Appetite loss

228

2.22 (1.33, 3.70)

2.69 (1.54, 4.69)

2.10 (1.21, 3.65)

0.72

 Constipation

229

3.69 (2.09, 6.52)

4.36 (2.35, 8.09)

3.62 (1.95, 6.69)

0.86

 Diarrhea

231

2.95 (1.77, 4.91)

2.26 (1.30, 3.95)

2.35 (1.36, 4.07)

0.48

 Financial Problems

231

4.46 (2.56, 7.77)

5.96 (3.26, 10.90)

3.29 (1.81, 5.95)

0.19

EORTC QLQ-BR23, LS means (95% CI)b

Functioning

 Body image

231

36.03 (24.05, 54.00)

34.95 (22.49, 54.30)

32.14 (20.83, 49.58)

0.58

 Sexual functioning

209

2.69 (1.53, 4.71)

2.57 (1.43, 4.65)

5.34 (3.04, 9.39)

0.007

 Sexual enjoyment

69

16.89 (4.80, 59.47)

9.65 (3.14, 29.62)

11.54 (3.34, 39.90)

0.56

 Future perspective

231

17.83 (10.65, 29.83)

18.04 (10.29, 31.60)

19.72 (11.35, 34.24)

0.70

Symptom

 Systematic therapy side effects

231

21.59 (16.54, 28.19)

23.55 (17.62, 31.49)

19.06 (14.32, 25.36)

0.29

 Breast symptoms

231

12.45 (8.04, 19.28)

10.06 (6.25, 16.20)

10.42 (6.52, 16.65)

0.52

 Arm symptoms

231

18.20 (12.41, 26.69)

21.04 (13.86, 31.93)

17.92 (11.89, 27.02)

0.83

 Upset by hair loss

157

17.28 (8.92, 33.50)

14.78 (7.09, 30.83)

17.59 (8.60, 36.00)

0.90

  1. MET metabolic equivalent, EORTC QLQ-C30 European organization for research and treatment of cancer quality of life questionnaire core 30, LS least-squares, CI confidence interval, EORTC QLQ-BR23 European organization for research and treatment of cancer quality of life questionnaire breast cancer module 23
  2. aP for trend was calculated using the median value of each tertile category as a continuous variable
  3. bAdjusted for age (year: continuous), energy intake (kcal/day: continuous), dietary supplement use (yes, no), education level (high school or less, college or more), marital status (married or cohabitated, unmarried or divorced or widowed), time since surgery (6 month – 1 year, 1 year - 5 years, ≥5 years), stage (I, II, or III), and center
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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