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Table 3 Healthcare costs per person per montha in patients with NVAF treated with dabigatran or warfarin

From: Healthcare utilization and costs for patients initiating Dabigatran or Warfarin

Outcome Dabigatran Warfarin P valueb  
Total Cost, mean (95% CI)
 Unadjusted GLM Mean $2362 ($2213, $2521) $2204 ($2065, $2352) 0.1398
 Adjusted GLM Meand $2381 ($2106, $2700) $2183 ($1929, $2481) 0.0967
Total Pharmacy Cost, mean (95% CI)
 Unadjusted GLM Mean $509 ($488, $531) $251 ($240, $262) <.0001
 Adjusted GLM Meand $510 ($470, $555) $250 ($230, $273) <.0001
Total Medical Cost, mean (95% CI)
 Unadjusted GLM Mean $1903 ($1757, $2060) $1973 ($1823, $2135) 0.5276
 Adjusted GLM Meand $1912 ($1646, $2231) $1956 ($1683, $2286) 0.5500
Hospital-related All-Cause Medical Cost, mean (95% CI)
 Unadjusted GLM Mean $1534 ($1283, $1833) $1596 ($1338, $1903) 0.7552
 Adjusted GLM Meand $1094 ($821, $1480) $1137 ($851, $1539) 0.6607
ER related All-Cause Medical Cost, mean (95% CI)
 Unadjusted GLM Mean $73 ($65, $83) $82 ($73, $92) 0.2036
 Adjusted GLM Meand $72 ($58, $91) $83 ($66, $104) 0.0967
Physician office visits related All-Cause Medical Cost, mean (95% CI)
 Unadjusted GLM Mean $285 ($269, $303) $287 ($270, $305) 0.8929
 Adjusted GLM Meand $282 ($252, $317) $289 ($258, $326) 0.3792
Outpatient visits related All-Cause Medical Cost, mean (95% CI)
 Unadjusted GLM Mean $399 ($361, $441) $360 ($325, $398) 0.1554
 Adjusted GLM Meand $396 ($327, $482) $362 ($300, $445) 0.3120
  1. CI confidence interval, GLM generalized linear mean
  2. aPer-patient-per-month (PPPM) was calculated at the patient level (total costs divided by follow-up months), and summary statistics were derived from this measure
  3. b P values derived using a generalized linear model (GLM) with log link function and gamma distribution; Service location specific costs were increased by a constant of $1 to account for zero cost in the log cost model
  4. dadjusted for age, gender, race, CHADS2 score and HEMORR2HAGES score