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Table 1 Demographic and clinical characteristics of patients with NVAF treated with dabigatran or warfarin

From: Healthcare utilization and costs for patients initiating Dabigatran or Warfarin

  Pre-PSM Post-PSM
Measure Dabigatran Warfarin P value Dabigatran Warfarin P value
N 1127 3234   1110 1110  
Age, years
 Mean ± SD 75.0 ± 6.9 75.3 ± 7.4 0.3414 75.1 ± 6.9 75.0 ± 7.0 0.5682
 Median, [Min – Max] 75 [42–89] 76 [40–89] 75 [42–89] 75 [46–89]
 Male, n (%) 579 (51.4) 1663 (51.4) 0.9783 569 (51.3) 574 (51.7) 0.8318
Race/Ethnicity, n (%)
 White 1043 (92.5) 2908 (89.9) 0.0093 1028 (92.6) 1000 (90.1) 0.0345
 Other 84 (7.5) 326 (10.1) 82 (7.4) 110 (9.9)
Geographic Region, n (%)
 Northeast 27 (2.4) 82 (2.5) <0.0001 27 (2.4) 23 (2.1) 0.4615
 Midwest 254 (22.5) 1004 (31.0) 254 (22.9) 254 (22.9)
 South 764 (67.8) 1868 (57.8) 747 (67.3) 768 (69.2)
 West 82 (7.3) 280 (8.7) 82 (7.4) 65 (5.9)
Baseline Deyo-Charlson Comorbidity Index (DCI) score 2.1 ± 2.1 2.9 ± 2.5 <0.0001 2.1 ± 2.1 2.1 ± 2.0 0.5809
Baseline Elixhauser Comorbidity index (ECI) score 4.4 ± 2.5 5.5 ± 2.7 <0.0001 4.4 ± 2.5 4.5 ± 2.4 0.3789
Baseline stroke risk
 CHADS2 stroke risk score 2.3 ± 1.2 2.6 ± 1.2 <0.0001 2.3 ± 1.2 2.3 ± 1.2 0.7783
 CHA2DS2-VASc stroke risk score 4.0 ± 1.5 4.3 ± 1.5 <0.0001 4.0 ± 1.5 4.0 ± 1.5 0.8061
Baseline bleeding risk 0.1780
 HEMORR2HAGES score 2.4 ± 1.5 2.9 ± 1.7 <0.0001 2.4 ± 1.5 2.4 ± 1.4
 Time from first AF to index (days) 20 ± 22 19 ± 22 0.0282 20 ± 22 18 ± 22 0.0559
Duration of follow-up (days)
 Mean ± SD 346 ± 62 339 ± 74 0.0010 346 ± 62 343 ± 68 0.3329
 Median [Range] 365 [42–365] 365 [9–365]   365 [42–365] 365 [11–365]  
Total HCRU pre-index, mean visits per patient [SD]
 Hospitalization 0.8 [0.7] 1.1 [0.9] <.0001 0.8 [0.7] 0.9 [0.7] 0.0183
 ER visit 0.7 [1.2] 0.8 [1.5] 0.3055 0.7 [1.3] 0.7 [1.1] 0.0603
 Physician office visit 12.4 [9.6] 12.3 [10.3] 0.7100 12.4 [9.7] 11.6 [9.2] 0.0293
 Outpatient visit 5.7 [6.8] 7.3 [14.0] <.0001 5.7 [6.8] 6.1 [11.6] 0.3758
  1. SD standard deviation, HCRU Healthcare Resource Utilization, ER emergency room