Skip to main content

Table 3 Discrimination of ASCQ-Me and PROMIS scores among levels of SCD severity

From: Sensitivity of alternative measures of functioning and wellbeing for adults with sickle cell disease: comparison of PROMIS® to ASCQ-Me℠

ASCQ-Me & PROMIS measures

# Items

Low

Medium

High

F-Stata

dfb error/total

ASCQ-Me Stiffness Impact

5

53.80

48.81

45.81

38.07***

485/487

PROMIS Physical Functioning

10

45.75

43.22

38.70

34.64***

483/485

PROMIS Pain Impact

6

53.83

57.46

60.69

29.61***

482/484

ASCQ-Me Pain Impact

5

53.26

48.88

46.30

28.06***

486/488

PROMIS Pain Behavior

7

53.46

57.06

60.57

27.47***

485/487

PROMIS Social Roles

7

49.27

45.89

43.26

19.79***

485/487

ASCQ-Me Social Impact

5

52.72

48.91

46.72

18.21***

473/475

PROMIS Social Activities

7

51.83

49.29

47.08

12.78***

484/486

ASCQ-Me Emotional Impact

5

51.84

49.75

47.04

11.81***

483/485

ASCQ-Me Sleep Impact

5

52.24

48.79

48.10

10.42***

487/489

PROMIS Fatigue

7

54.41

55.50

58.24

9.34***

484/486

PROMIS Depression

8

51.93

53.29

56.15

8.42**

485/487

PROMIS Sleep Disturbance

8

52.41

55.20

56.57

7.70**

486/488

ASCQ-Me Pain Episode Severity

3

48.38

50.09

52.10

6.38*

487/489

ASCQ-Me Pain Episode Freq.

2

48.31

50.33

51.99

6.32*

487/489

PROMIS Anxiety

7

52.27

53.49

55.04

4.24

486/488

PROMIS Sleep Impairment

8

53.37

53.92

55.34

1.93

486/488

  1. aF-statistic associated with one-way analysis of variance
  2. bDegrees of freedom (df). For the model this is always equal to 2
  3. ***p < 0.0001; **p < 0.001; *p < 0.003