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Table 2 Linear mixed modeling: synergistic effects of time, gender, and family cancer history on QOL-lung cancer specific symptoms

From: Women with family cancer history are at risk for poorer physical quality of life and lower self-efficacy: a longitudinal study among men and women with non-small cell lung cancer

Parameter Estimate SE df t P 95% Confidence Intervals
Lower Bound Upper Bound
Results for QOL-lung cancer physical symptoms: analysis with main effects only (no interaction terms)
Intercept 26.28 1.43 162.03 18.36 <.01 23.45 29.10
Emotional QOL (covariate) −0.18 0.04 99.57 −4.11 <.01 −0.27 −0.09
Social QOL (covariate) −0.13 0.05 99.33 −2.83 .01 −0.23 −0.04
Family cancer history 2.22 1.24 99.44 1.79 .08 −0.24 4.68
Gender −0.62 1.33 99.68 −0.47 .64 −3.27 2.02
Time −7.52 0.76 122.15 −9.85 <.01 −9.03 −6.01
Results for QOL-lung cancer physical symptoms: analysis with interaction terms
Intercept 25.96 1.40 164.12 18.60 <.01 23.21 28.72
Emotional QOL (covariate) −0.16 0.04 99.88 −3.68 <.01 −0.24 −0.07
Social QOL (covariate) −0.14 0.05 99.53 −3.03 <.01 −0.23 −0.05
Family cancer history 2.97 1.41 162.46 2.10 .04 0.18 5.76
Gender 0.13 1.49 155.71 0.09 .93 −2.80 3.07
Gender * Family cancer history −1.94 1.41 162.53 −1.38 .17 −4.73 0.84
Time −7.61 0.75 121.39 −10.09 <.01 −9.10 −6.11
Time * Family cancer history −0.62 0.75 121.39 −0.82 .41 −2.11 0.88
Time * Gender −0.74 0.75 121.38 −0.98 .33 −2.23 0.75
Time * Gender* Family cancer history −1.32 0.75 121.38 −1.75 .08 −2.81 0.17
  1. Significant effects (p < .05) and trends for significant effects (p < .10) are marked in bold