|
Risk factor
|
OR
|
95% CI
|
p-value
|
|---|
|
OSA [Referent = None]
|
|
Mild
|
1.28
|
0.81; 2.01
|
0.29
|
|
Moderate/severe
|
1.19
|
0.76; 1.86
|
0.45
|
|
ESS
|
1.37
|
1.17; 1.60
|
<0.01
|
|
FSS
|
2.38
|
1.90; 2.99
|
<0.01
|
|
SF-12 PCS
|
1.79
|
1.47; 2.17
|
<0.01
|
|
Asthma
|
3.78
|
2.56; 5.59
|
<0.01
|
|
COPD
|
2.59
|
1.51; 4.41
|
<0.01
|
|
ILD
|
26.53
|
2.72; 258.46
|
<0.01
|
- Poor respiratory-specific QOL defined as the 20% highest AQ-20R scores, 11 through 20
- Mild OSA defined as apnea-hypopnea index greater than 5 but lower to 15. Moderate or severe obstructive sleep apnea defined as apnea-hypopnea index equal as or higher than 15
- ESS, FSS, PCS of the Short Form-12 are scaled per standard deviation units for comparability among scales. The PCS of the Short Form-12 is reversed scored for this analysis to indicate risk with poorer generic quality of life
- Age, sex, marital status and BMI were included in the model (other than younger age (OR 0.99, p = 0.03), none were statistically significantly associated with poorer QOL)
-
Abbreviations: BMI Body Mass Index, ESS Epworth Sleepiness Scale, FSS Fatigue Severity Scale, OR Odds Ratio, OSA Obstructive Sleep Apnea, PCS Physical Component Scale of the Short Form-12, QOL Quality of Life
