Risk factor | OR | 95% CI |
p-value |
|---|
OSA [Referent = None] |
 Mild | 1.28 | 0.81; 2.01 | 0.29 |
 Moderate/severe | 1.19 | 0.76; 1.86 | 0.45 |
ESS | 1.37 | 1.17; 1.60 | <0.01 |
FSS | 2.38 | 1.90; 2.99 | <0.01 |
SF-12 PCS | 1.79 | 1.47; 2.17 | <0.01 |
Asthma | 3.78 | 2.56; 5.59 | <0.01 |
COPD | 2.59 | 1.51; 4.41 | <0.01 |
ILD | 26.53 | 2.72; 258.46 | <0.01 |
- Poor respiratory-specific QOL defined as the 20% highest AQ-20R scores, 11 through 20
- Mild OSA defined as apnea-hypopnea index greater than 5 but lower to 15. Moderate or severe obstructive sleep apnea defined as apnea-hypopnea index equal as or higher than 15
- ESS, FSS, PCS of the Short Form-12 are scaled per standard deviation units for comparability among scales. The PCS of the Short Form-12 is reversed scored for this analysis to indicate risk with poorer generic quality of life
- Age, sex, marital status and BMI were included in the model (other than younger age (OR 0.99, p = 0.03), none were statistically significantly associated with poorer QOL)
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Abbreviations: BMI Body Mass Index, ESS Epworth Sleepiness Scale, FSS Fatigue Severity Scale, OR Odds Ratio, OSA Obstructive Sleep Apnea, PCS Physical Component Scale of the Short Form-12, QOL Quality of Life
