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Table 1 Demographic and health characteristics of respondents with IBS-D (diagnosed and undiagnosed) and controls

From: Health-related quality of life, work productivity, and indirect costs among patients with irritable bowel syndrome with diarrhea

 

Total n = 66,491

IBS-D, diagnosed n = 842

IBS-D, undiagnosed n = 260

Controls n = 65,389

p-value

Age, mean (SD)

48.72 (16.61)

50.39 (15.79)a

43.05 (14.40)b

48.72 (16.62)c

<0.001

Charlson Comorbidity Index, mean (SD)

0.42 (0.99)

0.72 (1.23)a

0.75 (1.50)a

0.41 (0.98)b

<0.001

Female, n (%)

33377 (50.2)

510 (60.6)a

169 (65.0)a

32698 (50.0)b

 

Race/ethnicity, n (%)

    

<0.001

 Non-Hispanic White

47700 (71.7)

712 (84.6)a

180 (69.2)b

46808 (71.6)b

 

 Non-Hispanic Black

7857 (11.8)

31 (3.7)a

28 (10.8)b

7798 (11.9)b

 

 Hispanic

5603 (8.4)

49 (5.8)a

27 (10.4)b

5527 (8.5)b

 

 Other ethnicity

5331 (8.0)

50 (5.9)a

25 (9.6)b

5256 (8.0)b

 

Education, n (%)

    

0.069

  < 4-year degree

39657 (59.6)

496 (58.9)a

173 (66.5)b

38988 (59.6)a

 

  ≥ 4-year degree

26834 (40.4)

346 (41.1)a

87 (33.5)b

26401 (40.4)a

 

Annual household income, n (%)

    

0.008

  < $25 k

12750 (19.2)

161 (19.1)a

65 (25.0)b

12524 (19.2)a

 

 $25–50 k

17775 (26.7)

215 (25.5)a

80 (30.8)a

17480 (26.7)a

 

 $50–75 k

13037 (19.6)

189 (22.4)a

54 (20.8)a,b

12794 (19.6)b

 

  ≥ $75 k

17369 (26.1)

214 (25.4)a

46 (17.7)b

17109 (26.2)a

 

 Declined to answer

5560 (8.4)

63 (7.5)a

15 (5.8)a

5482 (8.4)a

 

Labor force participation, n (%)

    

0.424

 Yes

35636 (53.6)

433 (51.4)a

142 (54.6)a

35061 (53.6)a

 

 No

30855 (46.4)

409 (48.6)a

118 (45.4)a

30328 (46.4)a

 

Body mass index, n (%)

    

<0.001

 Underweight (<18.5)

1231 (1.9)

11 (1.3)a

3 (1.2)a

1217 (1.9)a

 

 Normal weight (18.5–24.99)

20894 (31.4)

228 (27.1)a

76 (29.2)a,b

20590 (31.5)b

 

 Overweight (25–29.99)

21347 (32.1)

243 (28.9)a

68 (26.2)a

21036 (32.2)b

 

 Obese (≥30)

21265 (32.0)

341 (40.5)a

111 (42.7)a

20813 (31.8)b

 

 Unknown

1754 (2.6)

19 (2.3)a

2 (0.8)a

1733 (2.7)a

 
  1. For pairwise comparisons, values in the same row not sharing the same subscript letter (a, b, or c) are significantly different at p < 0.05
  2. Abbreviations: IBS-D irritable bowel syndrome with diarrhea, SD standard deviation