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Table 3 EQ-5D items and scores at baseline and pooled over time

From: Association between work time loss and quality of life in patients with Herpes Zoster: a pooled analysis of the MASTER studies

Variable Baseline Pooled visitsc
Work time lossa No work time loss Overallb p-value Work time lossa No work time loss Overallb p-value
Total nd 247 147 428 - 786 2148 3738  
Mobility, n (%)
 I have no problems in walking 174 (70.4) 117 (79.6) 318 (74.3)   554 (71.9) 1876 (89.7) 3019 (80.9)  
 I have some problems in walking 65 (26.3) 29 (19.7) 99 (23.1)   202 (26.2) 184 (8.8) 553 (14.8)  
 I am confined to a bed 5 (2.0) 0 (0.0) 5 (1.2) 0.051 8 (1.0) 4 (0.2) 13 (0.3) <0.001
 Not available 3 (1.2) 1 (0.7) 6 (1.4)   7 (0.9) 27 (1.3) 147 (3.9)  
Self-care, n (%)
 I have no problems in self-care 191 (77.3) 132 (89.8) 351 (82.0)   631 (81.8) 1988 (95.1) 3260 (87.4)  
 I have some problems washing and dressing 49 (19.8) 13 (8.8) 66 (15.4)   125 (16.2) 71 (3.4) 310 (8.3)  
 I am unable to wash and dress myself 4 (1.6) 1 (0.7) 5 (1.2) 0.005 8 (1.0) 5 (0.2) 15 (0.4) <0.001
 Not available 3 (1.2) 1 (0.7) 6 (1.4)   7 (0.9) 27 (1.3) 147 (3.9)  
Usual activities, n (%)
 I have no problems with performing usual activities 124 (50.2) 102 (69.4) 249 (58.2)   375 (48.6) 1773 (84.8) 2695 (72.2)  
 I have some problems performing usual activities 103 (41.7) 41 (27.9) 153 (35.7)   357 (46.3) 283 (13.5) 821 (22.0)  
 I am unable to perform usual activities 17 (6.9) 3 (2.0) 20 (4.7) 0.001 32 (4.2) 8 (0.4) 69 (1.8) <0.001
 Not available 3 (1.2) 1 (0.7) 6 (1.4)   7 (0.9) 27 (1.3) 147 (3.9)  
Pain/Discomfort, n (%)
 I have no pain or discomfort 54 (21.9) 45 (30.6) 110 (25.7)   197 (25.6) 1379 (65.9) 1955 (52.4)  
 I have moderate pain or discomfort 142 (57.5) 84 (57.1) 245 (57.2)   459 (59.5) 655 (31.3) 1428 (38.3)  
 I am extreme pain or discomfort 48 (19.4) 17 (11.6) 67 (15.7) 0.044 108 (14.0) 30 (1.4) 202 (5.4) <0.001
 Not available 3 (1.2) 1 (0.7) 6 (1.4)   7 (0.9) 27 (1.3) 147 (3.9)  
Anxiety/Depression, n (%)
 I am not anxious or depressed 122 (49.4) 88 (59.9) 230 (53.7)   381 (49.4) 1672 (80.0) 512 (58.9)  
 I am moderately anxious or depressed 96 (38.9) 49 (33.3) 156 (36.4)   325 (42.2) 367 (17.6) 910 (24.4)  
 I am extremely anxious or depressed 26 (10.5) 9 (6.1) 36 (8.4) 0.097 58 (7.5) 25 (1.2) 110 (2.9) <0.001
 Not available 3 (1.2) 1 (0.7) 27 (3.1)   7 (0.9) 27 (1.3) 147 (3.9)  
EQ-5D summary scores based on UK weight
n 244 146 422   764 2064 3585  
 Mean (SD) 0.6 (0.4) 0.7 (0.3) 0.6 (0.3) 0.001 0.6 (0.3) 0.9 (0.2) 0.8 (0.3) <0.001
VAS, mm
n 244 145 421   763 2059 3572  
 Mean (SD) 66.7 (23.7) 71.1 (20.5) 68.5 (22.4) 0.106 68.1 (22.6) 86.5 (16.6) 80.3 (21.0) <0.001
  1. SD standard deviation, VAS visual analogue scale, WPQ Work and Productivity Questionnaire
  2. aPatients with Work Time Loss were defined as those who reported missing work due to their shingles episode (entire day or part of a day) at baseline, or at any of the follow-up visits (Visits 2–10) as assessed by the WPQ
  3. b34 patients did not have information on Work Time Loss Category
  4. cVisits 1–10
  5. dTotal n’s are based on cumulative visits