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Table 3 Decrease in Quality-adjusted Life Years (QALY) throughout remainder of lifetime due to Major Depressive Disorder (MDD) and to Mild Depression, U.S. Adults Aged 65 Years and Older

From: Incremental decreases in quality-adjusted life years (QALY) associated with higher levels of depressive symptoms for U.S. Adults aged 65 years and older

PHQ-9 score Depression severity categories Number QALYa S.E. Lossb S.E. % Loss
0–9 No MDD 3,357 12.7 1.1 Ref - -
10–27 MDDc 173 4.4 0.9 8.3 1.2 65%
  Subcategories of MDD       
10–14 Moderate 122 4.7 0.7 8.0 1.1 63%
15–27 Moderately severe/severe 51 3.3 1.3 9.4 1.6 74%
0–4 None-minimal 2,863 14.0 1.4 Ref - -
5–9 Mild depression 494 7.8 1.0 6.2 1.3 44%
5–27 Mild depression or MDD 667 6.5 0.8 7.5 1.3 54%
  1. a Quality-adjusted life years (QALY) throughout remainder of lifetime, adjusted for age and sex in subgroups
  2. b Decrease in QALY for higher levels depressive symptoms vs. lower level depressive symptoms
  3. c Major depressive disorder (MDD)