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Table 6 MID in case of deterioration and improvement of HRQOL for both QLQ-C30 and QLQ-BR23 questionnaires after three and six months

From: Impact of the occurrence of a response shift on the determination of the minimal important difference in a health-related quality of life score over time

 

Deterioration of HRQOL

Improvement of HRQOL

Observed changes

Adjusted changes

Observed changes

Adjusted changes

QLQ-BR23 QLQ - C30

 After 3 months

5–26

8–19

0.3–10

0.6–4

 After 6 months

0.5–10

4–18

0.8–7

0–7

 After 3 months

7–20

7–18

2–15

0–7

 After 6 months

0.4–4

6–11

0.7–2

0–4