Table 1 Baseline characteristics of RA patients and the healthy controls
Variables | Cases (n = 131) | Controls (n = 104) | p |
|---|---|---|---|
Gender, female, N (%) | 112 (85.5) | 88 (84.6) | 0.79 |
BMI (kg/m2), Mean ± SD | 22.5 ± 3.12 | 22.84 ± 2.81 | 0.432 |
Age (years), Mean ± SD | 54.5 ± 11.5 | 54.77 ± 11.20 | 0.851 |
Monthly income (yuan), N (%) | Â | Â | 0.973 |
 <1000 | 67 (51.1) | 55 (52.9) |  |
 1000-3000 | 47 (35.9) | 35 (33.7) |  |
 3000-5000 | 13 (9.9) | 10 (9.6) |  |
 >5000 | 4 (3.1) | 4 (3.8) |  |
Marital status, N (%) | Â | Â | 0.411 |
 Single | 7 (5.3) | 11 (10.6) |  |
 Married | 118 (90.1) | 90 (86.5) |  |
 Divorced | 1 (0.8) | 1 (1.0) |  |
 Widowed | 5 (3.8) | 2 (1.9) |  |
Education, N (%) | Â | Â | 0.571 |
 ≤9 years | 93 (71.0) | 70 (76.9) |  |
 >9 years | 38 (29.0) | 34 (23.1) |  |
Occupation, N (%) | Â | Â | 0.757 |
 Employed | 102 (77.9) | 80 (80.8) |  |
 Unemployed | 29 (22.1) | 24 (19.2) |  |
Alcohol use, yes, N (%) | 24 (18.3) | 19 (18.3) | 1.000 |
Smoking use, yes, N (%) | 10 (7.6) | 10 (9.6) | 0.642 |
Disease duration (years), Mean ± SD | 8.7 ± 9.1 |  |  |
Family history, yes, N (%) | 10 (7.6) | Â | Â |
Medications use, N (%) | Â | Â | Â |
 NSAIDs | 692 (52.7) |  |  |
 Synthetic DMARDs | 129 (98.5) |  |  |
 Biologic DMARDs | 11 (8.4) |  |  |
 Glucocorticoid | 62 (47.3) |  |  |
ESR (mm/h), Mean ± SD | 28.47 ± 27. 64 |  |  |
CRP (mg/L), Mean ± SD | 16.61 ± 24.51 |  |  |
RF positive, N (%) | 102 (77.9) | Â | Â |
anti-CCP positive, N (%) | 91 (69.5) | Â | Â |
DAS28, Mean ± SD | 3.96 ± 1.44 |  |  |
HAQ-DI, Mean ± SD | 0.50 ± 0.61 |  |  |
Total pain (VAS), Mean ± SD | 4.32 ± 2.76 |  |  |
Nocturnal pain (VAS), Mean ± SD | 3.95 ± 3.22 |  |  |
HADS-A, Mean ± SD | 9.12 ± 2.79 |  |  |
HADS-D, Mean ± SD | 8.74 ± 2.46 |  |  |