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Table 3 Multivariate analysis for a significant functional deterioration

From: Orthostatic intolerance symptoms are associated with depression and diminished quality of life in patients with postural tachycardia syndrome

(n = 107) Depression Diminished physical QOL Diminished mental QOL
  OR 95 % CI P value OR 95 % CI P value OR 95 % CI P value
Total OIQ score a
 OIQ scores 0–9   Reference    Reference    Reference  
 OIQ scores 10–19 6.190 2.021–18.958 0.001* 3.103 0.748–12.883 0.119 4.686 1.583–13.882 0.005*
 OIQ scores ≥20 14.300 4.083–50.078 <0.001* 13.144 3.037–56.891 0.001* 10.392 3.071–35.163 <0.001*
OIQ score items b
 Nausea     2.501 1.631–3.834 <0.001*    
 Chest discomfort 1.717 1.130–2.610 0.011*       
 Concentration difficulties 1.470 1.027–2.104 0.035*     1.756 1.290–2.389 <0.001*
  1. Abbreviations: OIQ orthostatic intolerance questionnaire, QOL quality of life
  2. a Ordinal regression analysis was performed. Basic demographics (age, sex, body mass index, maximal HR increment) and total OIQ scores were analyzed
  3. b Logistic regression analysis was performed. Basic demographics (age, sex, body mass index, maximal HR increment) and OIQ items with P < 0.1 were analyzed using the backward Wald elimination method (cutoff P ≥ 0.05). The final OIQ items remained in the models are displayed
  4. *p < 0.05