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Table 3 Multivariate analysis for a significant functional deterioration

From: Orthostatic intolerance symptoms are associated with depression and diminished quality of life in patients with postural tachycardia syndrome

(n = 107)

Depression

Diminished physical QOL

Diminished mental QOL

 

OR

95 % CI

P value

OR

95 % CI

P value

OR

95 % CI

P value

Total OIQ score a

 OIQ scores 0–9

 

Reference

  

Reference

  

Reference

 

 OIQ scores 10–19

6.190

2.021–18.958

0.001*

3.103

0.748–12.883

0.119

4.686

1.583–13.882

0.005*

 OIQ scores ≥20

14.300

4.083–50.078

<0.001*

13.144

3.037–56.891

0.001*

10.392

3.071–35.163

<0.001*

OIQ score items b

 Nausea

   

2.501

1.631–3.834

<0.001*

   

 Chest discomfort

1.717

1.130–2.610

0.011*

      

 Concentration difficulties

1.470

1.027–2.104

0.035*

   

1.756

1.290–2.389

<0.001*

  1. Abbreviations: OIQ orthostatic intolerance questionnaire, QOL quality of life
  2. a Ordinal regression analysis was performed. Basic demographics (age, sex, body mass index, maximal HR increment) and total OIQ scores were analyzed
  3. b Logistic regression analysis was performed. Basic demographics (age, sex, body mass index, maximal HR increment) and OIQ items with P < 0.1 were analyzed using the backward Wald elimination method (cutoff P ≥ 0.05). The final OIQ items remained in the models are displayed
  4. *p < 0.05