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Table 1 Demographics of study population

From: Metformin improved health-related quality of life in ethnic Chinese women with polycystic ovary syndrome

Characteristics All (n = 109) Subgroups
Normal weight
(BMI < 25 kg/m2)
(n = 48)
Overweight
(BMI 25 kg/m2) (n = 61)
Non-hyperandrogenism
(n = 22)
Hyperandrogenism
(n = 87)
  Mean ± SD Mean ± SD Mean ± SD Mean ± SD Mean ± SD
 Age (years) 28.3 ± 5.1 27.12 ± 4.47 29.3 ± 5.47 27.6 ± 4.9 28.0 ± 5.2
 BMI (kg/m2) 26.8 ± 6.4 21.1 ± 1.9 31.6 ± 4.6** 23.8 ± 4.9 27.6 ± 6.5*
 Systolic BP (mmHg) 121.9 ± 16.3 113.1 ± 12.3 129.2 ± 15.7** 110.3 ± 11.3 125.2 ± 16.1*
 Diastolic BP (mmHg) 76.4 ± 13.7 69.8 ± 9.7 81.9 ± 14.3** 69.4 ± 9.9 78.4 ± 14.1*
 mF-G score 3.2 ± 2.1 2.8 ± 2.3 3.5 ± 1.9 2.5 ± 1.5 3.4 ± 2.2
Hormones Mean ± SD Mean ± SD Mean ± SD Mean ± SD Mean ± SD
 TSH (μIU/mL) 1.72 ± 0.91 1.40 ± 0.72 2.00 ± 0.87* 1.49 ± 0.74 1.79 ± 0.95
 LH (mIU/mL) 8.78 ± 4.82 11.02 ± 5.40 6.78 ± 3.17** 11.28 ± 5.80 8.01 ± 4.25*
 FSH (mIU/mL) 5.29 ± 2.07 5.50 ± 1.93 5.10 ± 2.20 5.24 ± 2.12 5.31 ± 2.08
 E2 (pg/mL)** 40.13 ± 41.74 36.41 ± 27.37 43.56 ± 51.73 40.21 ± 31.34 40.11 ± 44.56
 PRL (ng/mL) 9.12 ± 3.92 8.90 ± 3.59 9.31 ± 4.24 9.48 ± 4.01 9.01 ± 3.93
 TT (ng/mL) 0.58 ± 0.32 0.57 ± 0.37 0.59 ± 0.27 0.54 ± 0.24 0.59 ± 0.34
Glycemic parameters Mean ± SD Mean ± SD Mean ± SD Mean ± SD Mean ± SD
 2-h glucose (mg/dL) 113.2 ± 29.0 103.6 ± 26.9 121.2 ± 28.6* 105.4 ± 24.0 115.4 ± 30.1
 2-h insulin (μIU/mL) 89.8 ± 91.1 46.2 ± 25.3 126.9 ± 109.2** 52.8 ± 50.5 100.0 ± 97.3*
Clinical presentation n (%) n (%) n (%) n (%) n (%)
 Hirsutism 12 (16.2) 5 (14.7) 7 (17.5) 0 (0.0) 12 (20.7)
 Acne 36 (48.6) 16 (47.1) 20 (50.0) 0 (0.0) 36 (62.1)**
 Weight gain 33 (44.6) 11 (32.4) 22 (55.0) 5 (31.3) 28 (48.3)
 Hair loss 40 (54.1) 15 (44.1) 25 (62.5) 0 (0.0) 40 (69.0)**
 Impaired glucose intolerance 14 (18.9) 4 (11.8) 10 (25.0) 1 (6.3) 13 (22.4)
 Insulin resistance 54 (73.0) 20 (58.8) 34 (85.0)* 8 (50.0) 46 (79.3)*
  1. Abbreviations: BMI body mass index, BP blood pressure, LH luteinizing hormone, FSH follicle stimulating hormone, E2 estradiol, PRL prolactin, TT total testosterone, mF-G modified Ferriman-Gallwey, SD standard deviation
  2. *p < 0.05, **p < 0.001