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Table 1 Demographics of study population

From: Metformin improved health-related quality of life in ethnic Chinese women with polycystic ovary syndrome

Characteristics

All (n = 109)

Subgroups

Normal weight

(BMI < 25 kg/m2)

(n = 48)

Overweight

(BMI 25 kg/m2) (n = 61)

Non-hyperandrogenism

(n = 22)

Hyperandrogenism

(n = 87)

 

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

 Age (years)

28.3 ± 5.1

27.12 ± 4.47

29.3 ± 5.47

27.6 ± 4.9

28.0 ± 5.2

 BMI (kg/m2)

26.8 ± 6.4

21.1 ± 1.9

31.6 ± 4.6**

23.8 ± 4.9

27.6 ± 6.5*

 Systolic BP (mmHg)

121.9 ± 16.3

113.1 ± 12.3

129.2 ± 15.7**

110.3 ± 11.3

125.2 ± 16.1*

 Diastolic BP (mmHg)

76.4 ± 13.7

69.8 ± 9.7

81.9 ± 14.3**

69.4 ± 9.9

78.4 ± 14.1*

 mF-G score

3.2 ± 2.1

2.8 ± 2.3

3.5 ± 1.9

2.5 ± 1.5

3.4 ± 2.2

Hormones

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

 TSH (μIU/mL)

1.72 ± 0.91

1.40 ± 0.72

2.00 ± 0.87*

1.49 ± 0.74

1.79 ± 0.95

 LH (mIU/mL)

8.78 ± 4.82

11.02 ± 5.40

6.78 ± 3.17**

11.28 ± 5.80

8.01 ± 4.25*

 FSH (mIU/mL)

5.29 ± 2.07

5.50 ± 1.93

5.10 ± 2.20

5.24 ± 2.12

5.31 ± 2.08

 E2 (pg/mL)**

40.13 ± 41.74

36.41 ± 27.37

43.56 ± 51.73

40.21 ± 31.34

40.11 ± 44.56

 PRL (ng/mL)

9.12 ± 3.92

8.90 ± 3.59

9.31 ± 4.24

9.48 ± 4.01

9.01 ± 3.93

 TT (ng/mL)

0.58 ± 0.32

0.57 ± 0.37

0.59 ± 0.27

0.54 ± 0.24

0.59 ± 0.34

Glycemic parameters

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

 2-h glucose (mg/dL)

113.2 ± 29.0

103.6 ± 26.9

121.2 ± 28.6*

105.4 ± 24.0

115.4 ± 30.1

 2-h insulin (μIU/mL)

89.8 ± 91.1

46.2 ± 25.3

126.9 ± 109.2**

52.8 ± 50.5

100.0 ± 97.3*

Clinical presentation

n (%)

n (%)

n (%)

n (%)

n (%)

 Hirsutism

12 (16.2)

5 (14.7)

7 (17.5)

0 (0.0)

12 (20.7)

 Acne

36 (48.6)

16 (47.1)

20 (50.0)

0 (0.0)

36 (62.1)**

 Weight gain

33 (44.6)

11 (32.4)

22 (55.0)

5 (31.3)

28 (48.3)

 Hair loss

40 (54.1)

15 (44.1)

25 (62.5)

0 (0.0)

40 (69.0)**

 Impaired glucose intolerance

14 (18.9)

4 (11.8)

10 (25.0)

1 (6.3)

13 (22.4)

 Insulin resistance

54 (73.0)

20 (58.8)

34 (85.0)*

8 (50.0)

46 (79.3)*

  1. Abbreviations: BMI body mass index, BP blood pressure, LH luteinizing hormone, FSH follicle stimulating hormone, E2 estradiol, PRL prolactin, TT total testosterone, mF-G modified Ferriman-Gallwey, SD standard deviation
  2. *p < 0.05, **p < 0.001