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Table 4 Impact of clinical events on QoL measures among TAVR and SAVR patients

From: Quality of life among elderly patients undergoing transcatheter or surgical aortic valve replacement– a model-based longitudinal data analysis

  Quality of life Heart function Status of assistance
  EQ-5DIndex Five EQ-5D dimensions    
  (1) (2) (3) (4) (5) (6) (7) (8) (9)
  EQ-5DIndex Mobility Looking after myself Doing usual activities Having pain or discomfort Feeling worried, sad or unhappy NYHA score CCS score Status of assistance
  Point estimate Odds ratios from the ordered logistic regression model
Value at baseline 0.350*** 14.19*** 34.09*** 10.96*** 1.671* 2.751*** 2.457*** 1.398*** 10.82**
ASB life threatening/disabling −0.0463 12.68** 0.680 0.199 2.860 0.771 0.123 0.188 0.104
ASB major/minor 0.0985* 0.587 0.499 0.201** 0.182* 0.121* 0.762 0.673 0.342
NASB life threatening/disabling −0.447*** 584.6** 54.93 7.752 0.739 47.86* 1.410 1.591 86.32*
NASB major/minor −0.0199 1.188 0.688 0.597 1.311 0.573 1.180 0.813 4.088
VASC major/minor −0.00695 0.282 0.971 2.029 0.833 2.110 1.422 0.660 6.198
Stroke/TIA −0.161* 8.298** 1.358 4.179 6.661 2.561 0.343 0.380 0.958
AKIN 1 0.0659 1.270 1.104 0.357 0.430 0.742 0.547 0.601 0.718
AKIN 2 −0.158* 1.297 7.126 102.2** 0.814 0.340 81.36* 104.2** 21.79
AKIN 3 −0.177** 15.75*** 21.53** 7.419* 2.908 3.495 1.243 1.404 1.955
Arrhythmia −0.0377 2.393 3.153 1.954 1.817 2.200 3.490 0.234* 1.270
Other complications 0.0330 2.617 0.933 0.457 0.366 0.402 1.380 5.237* 1.057
Last follow-up before death −0.493*** 81.93*** 154.9*** 48.14** 29.90*** 32.98*** 2.877 1.335 144.8**
Second last follow-up before death −0.270*** 11.50** 23.04*** 5.949 15.13*** 11.13*** 1.542 1.786 12.95
Third from last follow-up before death −0.204*** 8.142 17.64** 4.509 1.996 3.602 3.855* 1.377 66.29**
Fourth from last follow-up before death −0.176*** 7.797* 11.09** 5.952 2.471 7.750** 1.581 2.016 23.22*
Fifth from last follow-up before death −0.150*** 4.843 13.36** 8.091 1.600 2.446 0.926 1.217 25.23*
Sixth from last follow-up before death −0.104* 1.800 3.205 2.907 3.803 2.932 1.259 1.081 35.30*
Overall trend −0.00165 1.085*** 1.045 0.966 1.044*** 0.983 1.056*** 1.020 1.088**
Month 1 post-discharge −0.0233 1.602 1.433 2.066* 1.465 1.130 1.370 1.599 2.774
Constant 0.528***         
N 2212 2246 2256 2254 2254 2219 2182 2022 1357
  1. * p < 0.05, ** p < 0.01, *** p < 0.001
  2. The EQ-5DIndex is a continuous variable between 0 and 1 (0 = worst state, 1 = best state). The 5 EQ-5D dimensions as shown in Model (2) to model (6) are order categorical variables (1 = no problems, 2 = some problems, 3 = extreme problems). Canadian Cardiovascular Society (CCS) Angina Grading Scale is an order categorical variable between 1 (angina only during strenuous or prolonged physical activity) and 4 (inability to perform any activity without angina). New York Heart Association (NYHA) Functional Classification is an order categorical variable between 1 (cardiac disease, but no symptoms and no limitation in ordinary physical activity) and 4 (severe limitations, experiences symptoms even while at rest). The current state of assistance is an order categorical variable with 1 (no external help or intra-familial help only), 2 (assisted living and/or home care services) and 3 (short or long-term care or temporal hospitalization). ASB access site bleeding, NASB non-access site bleeding, VASC vascular complication, AKIN acute kidney injury