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Table 3 Between-group differences and baseline adjustment when analyzing QoL measures among patients with AS

From: Quality of life among elderly patients undergoing transcatheter or surgical aortic valve replacement– a model-based longitudinal data analysis

  Quality of life Heart function Status of assistance
  EQ-5DIndex five EQ-5D dimensions    
  (1) (2) (3) (4) (5) (6) (7) (8) (9)
  EQ-5DIndex Mobiliy Looking after myself Doing usual activities Having pain or discomfort Feeling worried, sad or unhappy NYHA score CCS score Status of assistance
  Point estimate Odds ratios from the ordered logistic regression model
Value at baseline 0.321*** 7.314*** 18.30*** 9.356*** 2.222*** 2.756*** 2.419*** 1.378*** 9.049**
EuroSCORE at baseline −0.000761 1.029 1.046 1.040* 0.999 1.011 0.992 1.000 0.985
TAVR Reference Reference Reference Reference Reference Reference Reference Reference Reference
SAVR 0.0532 0.209** 0.754 0.396* 0.459** 0.413* 1.258 0.912 0.0441***
SAVRplus −0.112* 3.162 6.843 3.559 2.185 2.487 2.416 1.132 1.129
DRUG −0.180** 14.42*** 1.463 1.948 2.114 3.667*** 26.69*** 1.416 2.174
Last follow-up before death −0.536*** 111.5*** 291.0*** 149.0*** 34.40*** 53.33*** 4.141 1.816 123.2**
Second last follow-up before death −0.334*** 16.37** 31.55*** 8.390* 19.85*** 16.00*** 1.826 1.752 16.09*
Third from last follow-up before death −0.246*** 15.48* 30.99*** 9.799* 3.929 3.782 5.026* 1.817 55.18**
Fourth from last follow-up before death −0.225*** 9.108* 12.66*** 7.110 4.175 8.558** 1.670 2.307 24.06**
Fifth from last follow-up before death −0.157*** 6.018 15.68** 11.47* 1.822 2.491 0.985 1.371 16.51*
Sixth from last follow-up before death −0.108** 2.088 3.711 3.231 3.290 3.457 1.360 1.129 16.89
Overall trend −0.00140 1.087*** 1.041 0.967 1.043*** 0.978 1.051*** 1.021 1.071*
Month 1 post-discharge −0.0425** 2.139* 2.038* 2.282** 1.212 1.346 1.853* 1.047 3.206*
Constant 0.554***         
N 2159 2189 2193 2191 2191 2156 2119 1952 1317
  1. * p < 0.05, ** p < 0.01, *** p < 0.001
  2. The EQ-5DIndex is a continuous variable between 0 and 1 (0 = worst state, 1 = best state). The 5 EQ-5D dimensions as shown in Model (2) to model (6) are order categorical variables (1 = no problems, 2 = some problems, 3 = extreme problems). Canadian Cardiovascular Society (CCS) Angina Grading Scale is an order categorical variable between 1 (angina only during strenuous or prolonged physical activity) and 4 (inability to perform any activity without angina). New York Heart Association (NYHA) Functional Classification is an order categorical variable between 1 (cardiac disease, but no symptoms and no limitation in ordinary physical activity) and 4 (severe limitations, experiences symptoms even while at rest). The current state of assistance is an order categorical variable with 1 (no external help or intra-familial help only), 2 (assisted living and/or home care services) and 3 (short or long-term care or temporal hospitalization). The group SAVRplus includes 17 patients that underwent additional bypass grafting and/or mitral valve replacement