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Table 3 Between-group differences and baseline adjustment when analyzing QoL measures among patients with AS

From: Quality of life among elderly patients undergoing transcatheter or surgical aortic valve replacement– a model-based longitudinal data analysis

 

Quality of life

Heart function

Status of assistance

 

EQ-5DIndex

five EQ-5D dimensions

   
 

(1)

(2)

(3)

(4)

(5)

(6)

(7)

(8)

(9)

 

EQ-5DIndex

Mobiliy

Looking after myself

Doing usual activities

Having pain or discomfort

Feeling worried, sad or unhappy

NYHA score

CCS score

Status of assistance

 

Point estimate

Odds ratios from the ordered logistic regression model

Value at baseline

0.321***

7.314***

18.30***

9.356***

2.222***

2.756***

2.419***

1.378***

9.049**

EuroSCORE at baseline

−0.000761

1.029

1.046

1.040*

0.999

1.011

0.992

1.000

0.985

TAVR

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

SAVR

0.0532

0.209**

0.754

0.396*

0.459**

0.413*

1.258

0.912

0.0441***

SAVRplus

−0.112*

3.162

6.843

3.559

2.185

2.487

2.416

1.132

1.129

DRUG

−0.180**

14.42***

1.463

1.948

2.114

3.667***

26.69***

1.416

2.174

Last follow-up before death

−0.536***

111.5***

291.0***

149.0***

34.40***

53.33***

4.141

1.816

123.2**

Second last follow-up before death

−0.334***

16.37**

31.55***

8.390*

19.85***

16.00***

1.826

1.752

16.09*

Third from last follow-up before death

−0.246***

15.48*

30.99***

9.799*

3.929

3.782

5.026*

1.817

55.18**

Fourth from last follow-up before death

−0.225***

9.108*

12.66***

7.110

4.175

8.558**

1.670

2.307

24.06**

Fifth from last follow-up before death

−0.157***

6.018

15.68**

11.47*

1.822

2.491

0.985

1.371

16.51*

Sixth from last follow-up before death

−0.108**

2.088

3.711

3.231

3.290

3.457

1.360

1.129

16.89

Overall trend

−0.00140

1.087***

1.041

0.967

1.043***

0.978

1.051***

1.021

1.071*

Month 1 post-discharge

−0.0425**

2.139*

2.038*

2.282**

1.212

1.346

1.853*

1.047

3.206*

Constant

0.554***

        

N

2159

2189

2193

2191

2191

2156

2119

1952

1317

  1. * p < 0.05, ** p < 0.01, *** p < 0.001
  2. The EQ-5DIndex is a continuous variable between 0 and 1 (0 = worst state, 1 = best state). The 5 EQ-5D dimensions as shown in Model (2) to model (6) are order categorical variables (1 = no problems, 2 = some problems, 3 = extreme problems). Canadian Cardiovascular Society (CCS) Angina Grading Scale is an order categorical variable between 1 (angina only during strenuous or prolonged physical activity) and 4 (inability to perform any activity without angina). New York Heart Association (NYHA) Functional Classification is an order categorical variable between 1 (cardiac disease, but no symptoms and no limitation in ordinary physical activity) and 4 (severe limitations, experiences symptoms even while at rest). The current state of assistance is an order categorical variable with 1 (no external help or intra-familial help only), 2 (assisted living and/or home care services) and 3 (short or long-term care or temporal hospitalization). The group SAVRplus includes 17 patients that underwent additional bypass grafting and/or mitral valve replacement
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Health and Quality of Life Outcomes

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