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Table 7 Responsiveness of QDIS-7 and generic measures in comparisons across groups differing in self-evaluated outcomes during 9-month follow-up, all diseases combined

From: Standardizing disease-specific quality of life measures across multiple chronic conditions: development and initial evaluation of the QOL Disease Impact Scale (QDIS®)

Measure Mean change score by self-evaluated outcomea F-ratio RVb 95 % CIc
Much better Somewhat better Same Somewhat worse Much worse
  (N = 244) (N = 245) (N = 1181) (N = 282) (N = 37)    
QDIS-7d −2.76 −0.04 1.29 3.20 5.87 29.80 1.00 -
SF-8 PCSd 1.36 −0.71 −0.28 −3.22 −4.98 14.15 0.47 (0.24,0.85)
SF-8 MCSd 1.33 −0.47 0.14 −0.33 −0.91 2.06 0.07 (0.00,0.15)
  1. aSelf-evaluated change groups were defined as much better, somewhat better, about the same, somewhat worse, or much worse now in response to the question: “Compared to nine months ago, how much better or worse is your < DISEASE > now?”, where DISEASE was the pre-ID condition
  2. bRelative validity (RV) is computed as the ratio of the comparator F-statistic over the largest F-statistic for that comparison
  3. cComparator confidence intervals (CI) estimated using bootstrap
  4. dNorm-based scoring of all measures based on US general population norms (mean = 50, SD = 10). QDIS-7 scored so a higher score equals worse health; SF-8 scored so a higher score equals better health