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Table 3 Association of ppFEV1 and Pulmonary Exacerbations with EQ-5D Index and VAS

From: Impact of pulmonary exacerbations and lung function on generic health-related quality of life in patients with cystic fibrosis

Parameter Model 1: ppFEV1 Only Model 2: ppFEV1 + Any PE Model 3: ppFEV1 + PE Type
EQ-5D Index
 Intercept 0.670 (0.068)** 0.678 (0.067)** 0.686 (0.067)**
 ppFEV1 0.580 (0.193)** 0.561 (0.193)* 0.535 (0.193)*
 ppFEV1 squared −0.305 (0.135)** −0.294 (0.135)* −0.274 (0.135)*
 Any PE −0.026 (0.013)*
 PE (Hospitalization) −0.070 (0.020)*
 PE (No Hospitalization) 0.001 (0.016)
EQ-5D VAS
 Intercept 57.79 (2.38)** 58.46 (2.36)** 58.48 (2.36)**
 ppFEV1 32.14 (3.23)** 31.52 (3.21)** 31.49 (3.21)**
 Any PE −4.4 (1.08)**
 PE (Hospitalization) −3.82 (1.69)*
 PE (No Hospitalization) −4.75 (1.34)**
  1. Abbreviations: PE pulmonary exacerbation, ppFEV 1 percent predicted forced expiratory volume in 1 second, VAS visual analog scale
  2. *p < 0.05 **p < 0.001