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Table 3 Association of ppFEV1 and Pulmonary Exacerbations with EQ-5D Index and VAS

From: Impact of pulmonary exacerbations and lung function on generic health-related quality of life in patients with cystic fibrosis

Parameter

Model 1: ppFEV1 Only

Model 2: ppFEV1 + Any PE

Model 3: ppFEV1 + PE Type

EQ-5D Index

 Intercept

0.670 (0.068)**

0.678 (0.067)**

0.686 (0.067)**

 ppFEV1

0.580 (0.193)**

0.561 (0.193)*

0.535 (0.193)*

 ppFEV1 squared

−0.305 (0.135)**

−0.294 (0.135)*

−0.274 (0.135)*

 Any PE

−0.026 (0.013)*

 PE (Hospitalization)

−0.070 (0.020)*

 PE (No Hospitalization)

0.001 (0.016)

EQ-5D VAS

 Intercept

57.79 (2.38)**

58.46 (2.36)**

58.48 (2.36)**

 ppFEV1

32.14 (3.23)**

31.52 (3.21)**

31.49 (3.21)**

 Any PE

−4.4 (1.08)**

 PE (Hospitalization)

−3.82 (1.69)*

 PE (No Hospitalization)

−4.75 (1.34)**

  1. Abbreviations: PE pulmonary exacerbation, ppFEV 1 percent predicted forced expiratory volume in 1 second, VAS visual analog scale
  2. *p < 0.05 **p < 0.001