Skip to main content

Table 5 Relationship between percent reduction from baseline in BPI Sleep Interference by Pain and improvement on the PGIC

From: Relationship between pain relief, reduction in pain-associated sleep interference, and overall impression of improvement in patients with postherpetic neuralgia treated with extended-release gabapentin

  ≥30 % reduction in BPI Sleep Interference <30 % reduction in BPI Sleep Interference Difference p-value
(n = 301) (n = 171) % (95 % CI)
“Much” or “Very Much” improved on PGIC, n (%) 174 (57.8) 46 (26.9) 30.91 (22.23, 39.58) <0.0001
Not improved on PGICa, n (%) 127 (42.2) 125 (73.1) −30.91 (−39.58, −22.23) <0.0001
Difference, % (95 % CI) 15.61 (7.72, 23.50) −46.29 (−55.60, −36.80) n/a n/a
p-value 0.0001 <0.0001 n/a n/a
  1. aIncludes patients from other PGIC categories: Minimally Improved, No Change, Minimally Worse, Much Worse, Very Much Worse; n/a, not applicable