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Table 3 Relationship between percent reduction from baseline in BPI sleep interference by pain and percent reduction in VAS

From: Relationship between pain relief, reduction in pain-associated sleep interference, and overall impression of improvement in patients with postherpetic neuralgia treated with extended-release gabapentin

  ≥30 % reduction in VASa <30 % reduction in VASa Difference p-value
(n = 293) (n = 253) % (95 % CI)
≥30 % reduction in BPI Sleep Interference, n (%) 211 (72.0) 100 (39.5) 32.49 (24.57, 40.41) <0.0001
<30 % reduction in BPI Sleep Interference, n (%) 56 (19.1) 125 (49.4) −30.29 (−37.93, −22.66) <0.0001
Difference, % (95 % CI) 52.90 (46.07, 59.73) −9.88 (−18.50, −1.26) n/a n/a
p-value <0.0001 0.0253 n/a n/a
  1. aMissing data were excluded; number of patients does not add up to 100 %; n/a, not applicable