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Table 3 Mean RSCLa Subscale Scores by KPS

From: Patient-reported pain and other quality of life domains as prognostic factors for survival in a phase III clinical trial of patients with advanced breast cancer

KPS RSCL – Activity RSCL – Physical RSCL – Psych RSCL – HRQOL
  n Mean (SD) n Mean (SD) n Mean (SD) n Mean (SD)
Overallb 329 83.3 (22.65) 333 83.5 (12.37) 332 64.4 (23.76) 323 66.0 (24.14)
≤70 25 51.2 (27.11) 26 74.4 (14.21) 26 56.5 (26.78) 26 38.5 (28.19)
80 58 71.7 (26.25) 59 78.5 (12.27) 58 60.3 (23.31) 58 58.6 (22.13)
90 110 85.2 (18.62) 111 84.9 (11.75) 111 65.1 (24.19) 109 67.1 (22.39)
100 136 92.7 (14.32) 137 86.2 (11.17) 137 67.1 (22.67) 130 74.0 (20.54)
   p = 0.0001c   p < 0.0001c   p = 0.1630c   p < 0.0001c
  1. Activity: Activity level; Physical: Physical distress; Psych: Psychological distress
  2. HRQOL health-related quality of life; KPS Karnofsky Performance Status; RSCL Rotterdam Symptom Checklist; SD standard deviation
  3. a RSCL scores transformed to a range from 0 to 100, with 100 as best score
  4. b Overall patient numbers < 336 because not all answered every RSCL item
  5. c p-values derived from one-way analysis of variance