Table 6 LS mean of changes from baseline in FACT-B EWB score with 95 % CIs (final analysis set)

Follow-up

6 months

−0.00

−0.53 to 0.53

–

12 months

0.76

0.22–1.30

–

18 months

0.92

0.36–1.48

–

24 months

1.29

0.71–1.86

–

6–12 months

−0.76

−1.04 to −0.48

<.0001

6–18 months

−0.92

−1.26 to −0.58

<.0001

6–24 months

−1.29

−1.65 to −0.93

<.0001

12–18 months

−0.16

−0.46 to 0.14

.2895

12–24 months

−0.53

−0.88 to −0.18

.0033

18–24 months

−0.37

−0.67 to −0.07

.0172

Prior chemotherapies

Yes

1.54

0.96–2.12

–

No

−0.06

−0.64 to 0.53

–

Yes–No

1.60

1.05–2.14

<.0001

Age group

>60 years

1.01

0.38–1.64

–

≤60 years

0.47

−0.07–1.01

–

>60 years – ≤60 years

0.54

−0.03 to 1.10

.0613

Mastectomy

Yes

1.20

0.85–1.55

–

No

0.29

−0.68 to 1.25

–

Yes–No

0.91

−0.12 to 1.94

.0823

Axillary lymph-node dissection

Yes

0.48

−0.10 to 1.06

–

No

1.01

0.36–1.65

–

Yes–No

−0.53

−1.20–0.14

.1233