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Table 2 PGI and mean changes from baseline in NRS and EQ-5D utility scores

From: Estimation of minimal clinically important change of the Japanese version of EQ-5D in patients with chronic noncancer pain: a retrospective research using real-world data

 

n

PGI Effective

dNRS Week 4 (∆)

p

dEQ-5D Week 4 (∆)

p

Baseline

Week 4 (∆)

Baseline

Week 4 (∆)

Overall

710

614 (86.5)

7.1 [1.9]

2.7 [2.3]

<0.0001

0.51 [0.20]

0.16 [0.20]

<0.0001

Major the causal disease of pain (multiple allowed)

        

 Osteoarthritis

182

168 (92.3)

7.0 [2.0]

2.9 [2.3]

<0.0001

0.53 [0.15]

0.17 [0.19]

<0.0001

 Lumbago

285

253 (88.8)

7.4 [1.8]

2.9 [2.4]

<0.0001

0.47 [0.23]

0.19 [0.22]

<0.0001

 Rheumatoid arthritis

29

21 (72.4)

6.4 [2.1]

1.7 [2.0]

0.0002

0.51 [0.18]

0.10 [0.15]

0.0018

 Neck, shoulder and arm syndrome

44

38 (86.4)

7.5 [1.7]

2.8 [2.2]

<0.0001

0.61 [0.14]

0.12 [0.18]

<0.0001

 Postherpetic neuralgia

54

46 (85.2)

6.7 [2.1]

2.9 [2.1]

<0.0001

0.58 [0.17]

0.15 [0.16]

<0.0001

 Periarthritis scapulohumeralis

46

39 (84.8)

7.4 [1.8]

2.2 [1.7]

<0.0001

0.55 [0.13]

0.12 [0.16]

<0.0001

 Spinal stenosis

61

47 (77.0)

7.1 [2.0]

2.5 [2.6]

<0.0001

0.53 [0.10]

0.12 [0.16]

<0.0001

 Disk herniation

30

27 (90.0)

6.8 [1.8]

2.7 [2.4]

<0.0001

0.50 [0.19]

0.17 [0.20]

<0.0001

 Others

233

196 (84.1)

6.9 [2.0]

2.5 [2.6]

<0.0001

0.52 [0.18]

0.13 [0.20]

<0.0001

  1. dEQ-5D denotes change in EuroQol-5D, dNRS change in numeric rating scale, PGI physician’s global impression