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Table 1 Participant characteristics

From: Interpreting change from patient reported outcome (PRO) endpoints: patient global ratings of concept versus patient global ratings of change, a case study among osteoporosis patients

N (%) No recent fracture (N = 107) Recent fracture (N = 37) Total
(N = 144)
Age, years, mean (SD)
[min-max, years]
69.7 (8.70)
[52.0-88.8]
69.4 (9.70)
[51.3-87.9]
69.4 (9.70)
[51.3-88.8]
Education    
 Did not complete high school 5 (4.7 %) 3 (8.1 %) 8 (5.6 %)
 High school 31 (29.0 %) 12 (32.4 %) 43 (29.9 %)
 Some college 33 (30.8 %) 12 (32.4 %) 45 (31.2 %)
 College degree 25 (23.4 %) 4 (10.8 %) 29 (20.1 %)
 Graduate degree 13 (12.1 %) 6 (16.2 %) 19 (13.2 %)
Ethnicity    
 Asian 2 (1.9 %) 0 (0 %) 2 (1.4 %)
 Black 1 (0.9 %) 3 (8.1 %) 4 (2.8 %)
 Hispanic 4 (3.7 %) 2 (5.4 %) 6 (4.2 %)
 White or Caucasian 100 (93.5 %) 32 (86.5 %) 132 (91.7 %)
Employment    
 Employed full time 14 (13.1 %) 6 (16.2 %) 20 (13.9 %)
 Employed part time 8 (7.5 %) 0 (0 %) 8 (5.6 %)
 Retired 64 (59.8 %) 21 (56.8 %) 85 (59.0 %)
 Unemployed 1 (0.9 %) 0 (0 %) 1 (0.7 %)
 Looking after home/family 11 (10.3 %) 2 (5.4 %) 13 (9.0 %)
 Permanently unable to work 7 (6.5 %) 7 (18.9 %) 14 (9.7 %)
 Other 2 (1.9 %) 1 (2.7 %) 3 (2.1 %)
Disease duration
[min-max, years]
6.83 (4.80) n = 94
[0.45 – 19.8]
8.02 (6.75) n = 25
[0–30.6]
7.08 (5.26) n = 119
[0 – 30.6]
Time (months) since most recent fracture
[min-max, months]
123.9 (193.5) n = 53
[1.97 - 703.8]
0.75 (0.41) n = 37
[0–1.35]
73.3 (160.0) n = 90
[0–704.6]
Medication    
 Calcium 69 (64.5 %) 24 (64.9 %) 93 (64.6 %)
 Vitamin D 73 (68.2 %) 24 (64.9 %) 97 (67.4 %)
 Bisphosphonates 68 (63.6 %) 12 (32.4 %) 80 (55.6 %)
 Other 29 (27.1 %) 9 (24.3 %) 38 (26.4 %)
 Pain medicationsa 64 (59.8 %) 28 (75.7 %) 92 (63.9 %)
Upper/lower limb impediments   
 Osteoarthritis 42 (39.3 %) 14 (37.8 %) 56 (38.9 %)
 Hip 22 (20.6 %) 3 (8.1 %) 25 (17.4 %)
 Knee 32 (29.9 %) 10 (27.0 %) 42 (29.2 %)
 Ankle 5 (4.7 %) 3 (8.1 %) 8 (5.6 %)
 Shoulder 11 (10.3 %) 3 (8.1 %) 14 (9.7 %)
 Wrist/hand 25 (23.4 %) 9 (24.3 %) 34 (23.6 %)
 Other upper limb 12 (11.2 %) 3 (8.1 %) 15 (10.4 %)
 Other lower limb 14 (13.1 %) 6 (16.2 %) 20 (13.9 %)
 No upper/lower limb impediment 57 (53.3 %) 20 (54.1 %) 77 (53.5 %)
OPAQ-PF scores (Total 0–100)b   
 Mean (SD) 82.2 (21.1) 57.0 (26.1) 75.7 (24.9)
 Median (IQR) 92.0 (69.3–100) 58.7 (37.3–78.7) 83.3 (57.7–98.7)
 Min, max 28, 100 5.33, 100 5.33, 100
 N (%) max 31 (29.0 %) 1 (2.7 %) 32 (22.2 %)
  1. aincludes 8 patients who reported taking pain medications their clinicians were unaware of and 5 patients who did not report taking medications prescribed by their clinicians
  2. blower scores indicate greater impairment