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Table 1 Participant characteristics

From: Interpreting change from patient reported outcome (PRO) endpoints: patient global ratings of concept versus patient global ratings of change, a case study among osteoporosis patients

N (%)

No recent fracture (N = 107)

Recent fracture (N = 37)

Total

(N = 144)

Age, years, mean (SD)

[min-max, years]

69.7 (8.70)

[52.0-88.8]

69.4 (9.70)

[51.3-87.9]

69.4 (9.70)

[51.3-88.8]

Education

   

 Did not complete high school

5 (4.7 %)

3 (8.1 %)

8 (5.6 %)

 High school

31 (29.0 %)

12 (32.4 %)

43 (29.9 %)

 Some college

33 (30.8 %)

12 (32.4 %)

45 (31.2 %)

 College degree

25 (23.4 %)

4 (10.8 %)

29 (20.1 %)

 Graduate degree

13 (12.1 %)

6 (16.2 %)

19 (13.2 %)

Ethnicity

   

 Asian

2 (1.9 %)

0 (0 %)

2 (1.4 %)

 Black

1 (0.9 %)

3 (8.1 %)

4 (2.8 %)

 Hispanic

4 (3.7 %)

2 (5.4 %)

6 (4.2 %)

 White or Caucasian

100 (93.5 %)

32 (86.5 %)

132 (91.7 %)

Employment

   

 Employed full time

14 (13.1 %)

6 (16.2 %)

20 (13.9 %)

 Employed part time

8 (7.5 %)

0 (0 %)

8 (5.6 %)

 Retired

64 (59.8 %)

21 (56.8 %)

85 (59.0 %)

 Unemployed

1 (0.9 %)

0 (0 %)

1 (0.7 %)

 Looking after home/family

11 (10.3 %)

2 (5.4 %)

13 (9.0 %)

 Permanently unable to work

7 (6.5 %)

7 (18.9 %)

14 (9.7 %)

 Other

2 (1.9 %)

1 (2.7 %)

3 (2.1 %)

Disease duration

[min-max, years]

6.83 (4.80) n = 94

[0.45 – 19.8]

8.02 (6.75) n = 25

[0–30.6]

7.08 (5.26) n = 119

[0 – 30.6]

Time (months) since most recent fracture

[min-max, months]

123.9 (193.5) n = 53

[1.97 - 703.8]

0.75 (0.41) n = 37

[0–1.35]

73.3 (160.0) n = 90

[0–704.6]

Medication

   

 Calcium

69 (64.5 %)

24 (64.9 %)

93 (64.6 %)

 Vitamin D

73 (68.2 %)

24 (64.9 %)

97 (67.4 %)

 Bisphosphonates

68 (63.6 %)

12 (32.4 %)

80 (55.6 %)

 Other

29 (27.1 %)

9 (24.3 %)

38 (26.4 %)

 Pain medicationsa

64 (59.8 %)

28 (75.7 %)

92 (63.9 %)

Upper/lower limb impediments

  

 Osteoarthritis

42 (39.3 %)

14 (37.8 %)

56 (38.9 %)

 Hip

22 (20.6 %)

3 (8.1 %)

25 (17.4 %)

 Knee

32 (29.9 %)

10 (27.0 %)

42 (29.2 %)

 Ankle

5 (4.7 %)

3 (8.1 %)

8 (5.6 %)

 Shoulder

11 (10.3 %)

3 (8.1 %)

14 (9.7 %)

 Wrist/hand

25 (23.4 %)

9 (24.3 %)

34 (23.6 %)

 Other upper limb

12 (11.2 %)

3 (8.1 %)

15 (10.4 %)

 Other lower limb

14 (13.1 %)

6 (16.2 %)

20 (13.9 %)

 No upper/lower limb impediment

57 (53.3 %)

20 (54.1 %)

77 (53.5 %)

OPAQ-PF scores (Total 0–100)b

  

 Mean (SD)

82.2 (21.1)

57.0 (26.1)

75.7 (24.9)

 Median (IQR)

92.0 (69.3–100)

58.7 (37.3–78.7)

83.3 (57.7–98.7)

 Min, max

28, 100

5.33, 100

5.33, 100

 N (%) max

31 (29.0 %)

1 (2.7 %)

32 (22.2 %)

  1. aincludes 8 patients who reported taking pain medications their clinicians were unaware of and 5 patients who did not report taking medications prescribed by their clinicians
  2. blower scores indicate greater impairment