Table 2 PRO-CTCAE item intraclass correlation by tablet, IVRS and paper modes of administration

Anxiety (F)

0.77 (0.68–0.83)

0.76 (0.67–0.83)

0.72 (0.61–0.79)

0.78 (0.68–0.85)

Anxiety (S)

0.75 (0.65–0.82)

0.72 (0.62–0.80)

0.73 (0.63–0.80)

0.70 (0.58–0.80)

Anxiety (I)

0.69 (0.58–0.77)

0.74 (0.64–0.81)

0.68 (0.57–0.77)

0.83 (0.75–0.89)

Constipation (S)

0.71 (0.60–0.79)

0.76 (0.66–0.83)

0.80 (0.73–0.86)

0.83 (0.74–0.89)

Decreased appetite (S)

0.73 (0.62–0.80)

0.80 (0.72–0.86)

0.82 (0.73–0.87)

0.81 (0.71–0.87)

Decreased appetite (I)

0.78 (0.69–0.84)

0.80 (0.72–0.86)

0.70 (0.60–0.79)

0.80 (0.71–0.87)

Fatigue, tiredness, or lack of energy (S)

0.74 (0.64–0.81)

0.76 (0.67–0.83)

0.74 (0.64–0.81)

0.77 (0.66–0.85)

Fatigue, tiredness, or lack of energy (I)

0.65 (0.53–0.75)

0.70 (0.59–0.79)

0.60 (0.46–0.70)

0.79 (0.69–0.86)

Insomnia (S)

0.83 (0.76–0.88)

0.94 (0.92–0.96)

0.79 (0.71–0.85)

0.65 (0.50–0.76)

Insomnia (I)

0.76 (0.67–0.83)

0.84 (0.77–0.89)

0.81 (0.74–0.87)

0.72 (0.59–0.81)

Loose or watery stools (F)

0.80 (0.73–0.86)

0.81 (0.74–0.87)

0.76 (0.67–0.83)

0.55 (0.38–0.69)

Mouth or throat sores (S)

0.82 (0.75–0.87)

0.87 (0.82–0.91)

0.71 (0.61–0.79)

0.82 (0.73–0.88)

Mouth or throat sores (I)

0.55 (0.41–0.67)

0.62 (0.48–0.72)

0.61 (0.47–0.71)

0.81 (0.72–0.87)

Nausea (F)

0.87 (0.81–0.91)

0.90 (0.85–0.93)

0.87 (0.82–0.91)

0.79 (0.70–0.86)

Nausea (S)

0.85 (0.78–0.89)

0.87 (0.82–0.91)

0.86 (0.80–0.90)

0.84 (0.76–0.89)

Numbness/tingling in hands/feet (S)

0.89 (0.85–0.92)

0.89 (0.84–0.92)

0.86 (0.81–0.91)

0.80 (0.70–0.86)

Numbness/tingling in hands/feet (I)

0.81 (0.73–0.86)

0.85 (0.79–0.90)

0.80 (0.73–0.86)

0.55 (0.37–0.68)

Pain (F)

0.90 (0.86–0.93)

0.93 (0.90–0.95)

0.91 (0.87–0.94)

0.83 (0.75–0.89)

Pain (S)

0.88 (0.83–0.92)

0.89 (0.85–0.92)

0.86 (0.81–0.90)

0.82 (0.73–0.88)

Pain (I)

0.77 (0.68–0.84)

0.83 (0.77–0.88)

0.77 (0.68–0.83)

0.84 (0.76–0.89)

Sad or unhappy feelings (F)

0.77 (0.68–0.83)

0.80 (0.72–0.85)

0.76 (0.67–0.83)

0.73 (0.61–0.81)

Sad or unhappy feelings (S)

0.77 (0.69–0.84)

0.79 (0.71–0.85)

0.79 (0.71–0.85)

0.63 (0.48–0.75)

Sad or unhappy feelings (I)

0.69 (0.58–0.78)

0.70 (0.59–0.78)

0.72 (0.61–0.80)

0.76 (0.65–0.84)

Shortness of breath (S)

0.85 (0.79–0.89)

0.87 (0.82–0.91)

0.90 (0.85–0.93)

0.70 (0.56–0.80)

Shortness of breath (I)

0.84 (0.77–0.89)

0.73 (0.63–0.81)

0.72 (0.61–0.80)

0.66 (0.52–0.77)

Vomiting (F)

0.82 (0.75–0.87)

0.96 (0.94–0.97)

0.87 (0.82–0.91)

0.81 (0.72–0.88)

Vomiting (S)

0.82 (0.75–0.87)

0.92 (0.88–0.94)

0.83 (0.76–0.88)

0.79 (0.70–0.86)