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Table 4 Multiple regression showing predictors of health-related quality of life in patients with SCD

From: Health-related quality of life in patients with sickle cell disease in Saudi Arabia

  Physical functioning Role limitations due to physical health Role limitations due to emotional problems Vitality Emotional well being Social functioning Pain General health
Predictors B P B P B P B P B P B P B P B P
(Constant) 76.3   61.7   45.3   50.6   74.6   77.5   77.3   59.6  
Gender −3.1 0.278 −0.2 0.964 1.7 0.714 1.1 0.619 −0.6 0.801 1.9 0.503 4.6 0.126 2.9 0.113
Age −0.2 0.327 0.2 0.519 0.6 0.020* 0.3 0.036* 0.0 0.772 0.2 0.202 −0.1 0.704 0.0 0.834
University 4.9 0.077 10.9 0.009* 13.9 0.003* 5.3 0.013* 3.7 0.102 2.6 0.359 4.1 0.179 3.4 0.060
Married −3.8 0.191 −8.4 0.056 −15.7 0.001* −6.9 0.002* −5.2 0.029* −6.1 0.036* −5.7 0.069 −2.8 0.146
Employed 5.1 0.086 1.9 0.673 0.2 0.960 7.3 0.001* 3.5 0.139 3.9 0.190 6.8 0.036* 1.8 0.347
Obese −1.5 0.717 −3.7 0.555 3.0 0.667 −2.8 0.366 2.1 0.544 −6.1 0.143 −1.4 0.750 −1.0 0.711
Fever 3.2 0.241 −8.7 0.032* −5.6 0.212 −6.6 0.001* −3.0 0.162 −5.2 0.054 −4.2 0.148 −1.9 0.292
Skin redness −5.7 0.033* −10.9 0.008* −5.5 0.226 −2.5 0.220 −1.9 0.382 −3.5 0.203 −2.1 0.472 −4.3 0.016*
Swelling −8.1 0.003* −6.0 0.131 −7.1 0.108 −4.2 0.036* −3.4 0.111 −8.4 0.002* −14.4 0.001* −4.3 0.013*
Blood transfusion −6.7 0.046* −9.8 0.052 −12.9 0.022* −1.6 0.524 −0.9 0.726 −7.4 0.026* −8.3 0.024* −5.9 0.007*
Family history of anemia −2.8 0.620 −8.6 0.291 2.4 0.788 −5.2 0.208 −7.0 0.119 −6.2 0.239 −8.8 0.125 −2.1 0.564
Family support −3.7 0.381 −3.2 0.621 −3.3 0.652 1.1 0.730 −1.1 0.754 −2.1 0.638 −7.6 0.107 −4.0 0.160
Other Chronic disease −4.0 0.293 −5.5 0.328 −1.0 0.867 −6.7 0.019* −9.7 0.001* −10.1 0.008* −3.7 0.369 −0.7 0.786
Regular exercise 0.0 0.988 4.7 0.239 −1.3 0.764 5.6 0.005* 1.7 0.433 6.1 0.024* 7.5 0.009* 5.2 0.003*
Spleen removed 4.2 0.192 8.1 0.090 11.8 0.027* 0.9 0.716 −5.1 0.048* −3.1 0.326 2.2 0.514 2.3 0.267
F-value 3.2   3.6   2.8   5.4   3   4.3   5.7   4.1  
P-value 0.001   0.001   0.001   0.001   0.001   0.001   0.001   0.001  
R Square 0.12   0.13   0.10   0.18   0.11   0.15   0.18   0.15  
R 0.35   0.36   0.32   0.42   0.33   0.39   0.43   0.38  
  1. * Controlling for other predictors in model, predictor is significant at α = 0.05