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Table 2 Differences in health-related quality of life by socio-demographic and clinical characteristics (N = 629)

From: Health-related quality of life in patients with sickle cell disease in Saudi Arabia

  

Physical functioning

Role limitations due to physical health

Role limitations due to emotional problems

Vitality

  

Mean

SD

P

Mean

SD

P

Mean

SD

P

Mean

SD

P

Gender

Female

57.0

23.7

0.019

36.5

37.1

0.630

39.1

41.7

0.423

49.0

20.0

0.060

Male

52.3

22.5

 

35.0

34.5

 

41.8

38.5

 

46.0

17.4

 

Older age

No

55.5

23.4

0.472

36.1

35.4

0.767

39.0

39.2

0.218

48.0

18.8

0.484

 

Yes

53.5

22.7

 

34.9

39.1

 

45.1

46.1

 

46.6

20.2

 

University

No

53.3

22.9

0.004

32.9

34.9

0.002*

38.1

39.7

0.020

45.9

18.3

0.001*

Yes

59.5

23.5

 

43.8

37.7

 

47.1

42.1

 

53.2

19.4

 

Married

No

56.0

23.6

0.401

38.4

34.8

0.078

42.3

39.1

0.183

49.1

18.2

0.061

Yes

54.3

23.1

 

33.1

37.6

 

37.8

42.2

 

46.1

19.9

 

Employed

No

53.4

22.5

0.002*

35.7

36.0

0.379

39.6

39.9

0.283

45.6

18.6

0.001*

Yes

60.1

23.3

 

38.7

37.6

 

43.8

41.8

 

52.1

19.6

 

Obese

No

56.3

23.9

0.086

37.6

36.8

0.309

42.2

40.3

0.766

48.2

19.5

0.188

Yes

49.7

23.4

 

31.5

34.9

 

40.3

42.8

 

44.2

15.6

 

Fever

No

55.9

23.8

0.555

44.6

36.5

0.001*

46.5

41.8

0.002*

53.7

19.2

0.001*

Yes

54.7

23.1

 

30.0

34.8

 

35.8

39.2

 

43.9

17.9

 

Skin redness

No

57.5

22.6

0.001*

40.3

36.4

0.001*

42.7

40.6

0.040

50.3

19.3

0.001*

Yes

50.5

23.6

 

27.1

34.1

 

35.3

40.3

 

42.9

17.5

 

Swelling

No

59.2

22.9

0.001*

41.0

36.9

0.001*

44.8

41.5

0.002*

52.1

20.0

0.001*

Yes

51.2

22.9

 

29.7

34.1

 

34.7

39.0

 

42.9

16.9

 

History of blood transfusion

No

61.7

25.1

0.003*

47.9

37.1

0.001*

50.2

41.5

0.007

53.3

21.1

0.002*

Yes

53.7

22.8

 

33.6

35.4

 

37.9

40.0

 

46.6

18.5

 

Family history of anemia

No

53.3

19.6

0.547

38.5

37.5

0.623

44.2

41.1

0.480

51.7

17.5

0.102

Yes

55.4

23.5

 

35.9

36.1

 

40.1

40.5

 

47.2

19.1

 

Family support

No

57.7

21.3

0.424

35.9

40.0

0.983

45.2

47.2

0.469

46.7

22.2

0.659

Yes

54.8

23.6

 

35.8

35.9

 

39.9

40.0

 

48.0

18.7

 

Other Chronic disease

No

56.0

23.2

0.032

37.6

36.2

0.034

41.4

40.7

0.242

49.0

19.3

0.002*

Yes

50.4

22.7

 

29.1

34.6

 

36.1

39.3

 

42.4

17.2

 

Regular exercise

No

54.1

22.6

0.134

34.8

36.4

0.261

40.3

41.0

0.694

44.7

18.6

0.001*

Yes

57.3

24.6

 

38.3

35.1

 

38.9

39.4

 

53.5

18.5

 

Spleen removed

No

55.1

23.0

0.877

34.7

35.5

0.088

39.5

40.5

0.451

47.7

19.1

0.931

Yes

54.7

24.9

 

41.3

38.3

 

42.8

40.8

 

47.9

18.8

 
  1. *The factor is significant using Bonferroni correction cut-off at α/n = 0.05/15 = 0.003