From: Quality of life in polyneuropathy: association with biomarkers of small fiber impairment
Features | Patients with neuropathy |
---|---|
Men/Women | 38/23 |
Age (Mean ± SD) | 58.14±12.95 |
Mean duration of disease (Interquartile range) | 4 (1–6) |
Neurological examinations | |
Motor systema | |
Upper limbs | Proximal: 4.82 ± 0.59 / Distal: 4.68 ± 0.58 b |
Lower limbs | Proximal: 4.66 ± 0.84 / Distal: 4.42 ± 0.85 c |
Sensory system | |
Large-fiber sensory impairment | |
Impaired proprioception | 65.6 % |
Impaired vibration sensation at ankles | 65.6 % |
Small-fiber sensory impairment | |
Impaired pinprick sensation | 80.3 % |
Burning or tingling sensation | 77.0 % |
Other small fiber characteristics d | 8.2 % |
Autonomic system | |
Gastrointestinal symptoms | 32.8 % |
Genitourinary symptoms | 26.2 % |
Orthostatic hypotension | 29.5 % |
Sudomotor failure | 37.7 % |
Etiology | |
Diabetic polyneuropathy | 10 (16.4 %) |
Immune-related polyneuropathy e | 11 (18.0 %) |
Drug-induced polyneuropathy f | 4 ( 6.6 %) |
Inherited polyneuropathy g | 10 (16.4 %) |
Idiopathic polyneuropathy | 26 (42.6 %) |