Skip to main content

Table 1 Clinical profiles of patients with polyneuropathy

From: Quality of life in polyneuropathy: association with biomarkers of small fiber impairment

Features

Patients with neuropathy

Men/Women

38/23

Age (Mean ± SD)

58.14±12.95

Mean duration of disease (Interquartile range)

4 (1–6)

Neurological examinations

 

Motor systema

 

Upper limbs

Proximal: 4.82 ± 0.59 / Distal: 4.68 ± 0.58 b

Lower limbs

Proximal: 4.66 ± 0.84 / Distal: 4.42 ± 0.85 c

Sensory system

 

Large-fiber sensory impairment

 

Impaired proprioception

65.6 %

Impaired vibration sensation at ankles

65.6 %

Small-fiber sensory impairment

 

Impaired pinprick sensation

80.3 %

Burning or tingling sensation

77.0 %

Other small fiber characteristics d

8.2 %

Autonomic system

 

Gastrointestinal symptoms

32.8 %

Genitourinary symptoms

26.2 %

Orthostatic hypotension

29.5 %

Sudomotor failure

37.7 %

Etiology

 

Diabetic polyneuropathy

10 (16.4 %)

Immune-related polyneuropathy e

11 (18.0 %)

Drug-induced polyneuropathy f

4 ( 6.6 %)

Inherited polyneuropathy g

10 (16.4 %)

Idiopathic polyneuropathy

26 (42.6 %)

  1. a:Muscle strength: according to Medical Research Council (MRC) grade
  2. b:Proximal muscle of upper limbs included abduction muscle of the shoulder. Distal muscles of upper limbs included flexion and extension muscles of the wrist and grasp of the hand
  3. c:Proximal muscle of lower limbs included hip flexion muscle. Distal muscles of lower limbs included dorsiflexion and plantar flexion muscles of the ankle
  4. d:Electric shock–like or cold-like pain
  5. e:Chronic inflammatory demyelinating polyneuropathy (5), Sjögren syndrome (2), vasculitic neuropathy (2), Guillain-Barré syndrome (1), IgM paraproteinemic neuropathy (1)
  6. f:Chemotherapy induced neuropathy (3): docetaxel (2), cisplatin (1) and metronidazole induced neuropathy (1)
  7. g:Charcot-Marie-Tooth disease (3), familial amyloid polyneuropathy (7)