|
Initial cohort before PSA matching (N = 2,660)
|
Cohort after PSA matching (N = 1004)
|
---|
Variable
|
Non-intervention (n = 1,738)
|
Intervention (n = 922)
|
P
a
|
Non-intervention (n = 502)
|
Intervention (n = 502)
|
P
a
|
---|
Demographical data
| | | | | | |
Age, year
|
40.93 (10.31)
|
44.85 (8.6)
|
<0.001
|
44.52 (9.35)
|
44.81 (8.14)
|
0.609
|
Male gender, %
|
65.4%
|
60.2%
|
0.008
|
62.9%
|
64.3%
|
0.646
|
Physiologic parameters
| | | | | | |
Systolic blood pressure, mmHg
|
117.32(15.04)
|
116.68 (14.55)
|
0.293
|
117.03 (13.75)
|
117.57 (14.67)
|
0.549
|
Diastolic blood pressure, mmHg
|
73.43 (9.81)
|
73.45 (9.84)
|
0.946
|
73.34 (9.24)
|
73.86 (9.77)
|
0.387
|
Waist Circumference, cm
|
80.01 (10.18)
|
80.13 (9.59)
|
0.785
|
80.5 (9.3)
|
80.5 (9.8)
|
0.99
|
Body mass index, kg/m2
|
23.48 (3.32)
|
23.47 (3.15)
|
0.936
|
23.61 (2.86)
|
23.66 (3.21)
|
0.772
|
Serum sugar profiles
| | | | | | |
Fasting glucose, mg/dL
|
92.96 (13.83)
|
94.73 (15.76)
|
0.0033
|
94.22 (16.95)
|
94.22 (13.54)
|
1.000
|
Post-prandial glucose, mg/dL
|
101.51 (27.92)
|
103.73 (30.92)
|
0.139
|
104.16 (33.06)
|
103.75 (28.91)
|
0.846
|
HbA1c, %
|
5.43 (0.61)
|
5.53 (0.58)
|
0.048
|
5.41 (0.53)
|
5.51 (0.58)
|
0.063
|
Lipid Profiles
| | | | | | |
Total cholesterol, mg/dL
|
186.84 (32.90)
|
192.51 (33.42)
|
<0.001
|
191.16 (31.98)
|
192.06 (33.85)
|
0.666
|
HDL, mg/dL
|
54.07 (13.97)
|
56.10 (14.68)
|
0.006
|
55.42 (14.75)
|
55.76 (14.58)
|
0.713
|
LDL, mg/dL
|
118.46 (30.45)
|
124.86 (32.10)
|
<0.001
|
121.74 (29.55)
|
123.03 (31.11)
|
0.500
|
Triglyceride, mg/dL
|
110.05 (95.60)
|
115.96 (82.05)
|
0.151
|
112.83 (90.05)
|
113.45 (72.88)
|
0.917
|
Life style
| | | | | | |
Smoking, %
|
11.0%
|
17.0%
|
<0.001
|
16.5%
|
17.3%
|
0.736
|
Alcohol Consumption, %
|
7.7%
|
18.3%
|
<0.001
|
16.1%
|
15.7%
|
0.863
|
Exercise, %
|
23.9%
|
48.2%
|
<0.001
|
43.6%
|
45.6%
|
0.526
|
Cardiometabolic Outcomes
| | | | | | |
ATP III, number of MetS
|
1.28 (1.23)
|
1.49 (1.30)
|
<0.001
|
1.41 (1.27)
|
1.50 (1.27)
|
0.296
|
FRS, unit
|
4.57 (4.65)
|
4.97 (4.77)
|
0.132
|
4.68 (4.50)
|
4.76 (4.37)
|
0.809
|
eGFR, mL/min per 1.73 m2
|
86.05 (19.43)
|
84.30 (13.92)
|
0.028
|
83.51 (17.00)
|
83.88 (13.79)
|
0.704
|
-
adenotes either independent-sample t-test for continuous variable or chi-square test for categorical variable