From: Health related quality of life in adolescents with chronic fatigue syndrome: a cross-sectional study
CFS patients | Healthy control subjects | |
---|---|---|
Inclusion criteria: | Persisting or constantly relapsing fatigue lasting 3 months or more. | Age ≥ 12 years and < 18 years |
Functional disability resulting from fatigue to a degree that prevent normal school attendance | ||
Age ≥ 12 and < 18 years | ||
Exclusion criteria: | Another current process or chronic disease or demanding life event that might explain the fatigue | Another chronic disease |
Permanent use of pharmaceuticals (including hormones) | ||
Permanent use of pharmaceuticals (including hormones) possibly interfering with the measurements | ||
Permanently bed-ridden | ||
Positive pregnancy test | ||
Pheocromocytoma | ||
Evidence of reduced cerebral and/or peripheral circulation due to vessel disease | ||
Polyneuropathy | ||
Renal insufficiency | ||
Known hypersensitivity towards clonidine or inert substances (lactose, saccarose) in capsula | ||
Abnormal ECG (apart from ectopic beats) | ||
Supine heart rate < 50 beats/min | ||
Supine systolic blood pressure < 85 mmHg | ||
Upright systolic blood pressure fall > 30 mmHg |