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Table 1 Characteristics of the Mayo Clinic Biobank participants, for all and two HRQOL-related domains

From: Quantifying the importance of disease burden on perceived general health and depressive symptoms in patients within the Mayo Clinic Biobank

 

Overall cohort (n = 21,736)

Perceived general health

Depressive symptoms

Deficits (n = 2079)

Non-deficits (n = 19,657)

P-value*

Deficits (n = 1009)

Non-deficits (n = 20,727)

P-value**

Age,

   

<0.001

  

<0.001

  Median (25th – 75th % tiles)

62 (52,72)

63 (52,74)

62 (52,74)

55 (45,66)

63 (52,72)

Female %

57 %

58 %

57 %

0.52

61 %

57 %

0.03

Education

   

<0.001

  

<0.001

  High school or less

18 %

28 %

17 %

24 %

18 %

  Some college

33 %

40 %

32 %

40 %

33 %

  Bachelor degree

25 %

16 %

26 %

17 %

25 %

  Graduate school

24 %

16 %

25 %

19 %

24 %

Employment

   

<0.001

  

<0.001

  Not working - retired

34 %

41 %

33 %

25 %

34 %

  Not working - others

12 %

29 %

10 %

30 %

11 %

  Currently working

54 %

30 %

56 %

44 %

54 %

BMI

   

<0.001

  

<0.001

 Underweight

2.0 %

3.6 %

1.8 %

3.3 %

2.0 %

 Normal

28 %

24 %

29 %

25 %

28 %

 Overweight

37 %

26 %

37 %

28 %

37 %

 Obese

33 %

47 %

32 %

43 %

33 %

Smoking, ever %

42 %

54 %

41 %

<0.001

54 %

42 %

<0.001

Alcohol

   

<0.001

  

<0.001

 Never or less than once a month

42 %

64 %

39 %

57 %

41 %

 Once a week or less

23 %

17 %

24 %

19 %

23 %

 2+ a week

35 %

19 %

37 %

24 %

36 %

Disease burden (Number of self-reported diseases),

   

<0.001

  

<0.001

 Median (25th – 75th % tiles)

4 (2,6)

8 (5,10)

4 (2,6)

6 (4,9)

4 (2,6)

  1. *, **P-values comparing subjects with and without deficits in perceived general health (*), and depressive symptoms (**)