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Table 4 Prevalence of poor HRQOL based on vitamin D status after excluding participants comorbid chronic disease*

From: Association between serum vitamin D status and health-related quality of life (HRQOL) in an older Korean population with radiographic knee osteoarthritis: data from the Korean national health and nutrition examination survey (2010–2011)

 

Unadjusted

Model 1

Model 2

Model 3 ‡

 

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

EQ-VAS

        

Vit. D normal

Reference

 

Reference

 

Reference

 

Reference

 

Vit. D deficiency

2.253 (1.037-4.896)

0.040†

2.360 (1.120-4.976)

0.024†

2.291 (1.059-4.955)

0.035†

1.934 (0.810-4.617)

0.137

EQ-5D index

        

Vit. D normal

Reference

 

Reference

 

Reference

 

Reference

 

Vit. D deficiency

2.118 (0.942-4.762)

0.069

2.390 (1.085-5.266)

0.031†

2.324 (1.028-5.251)

0.043†

2.803 (1.172-6.703)

0.021†

  1. To control the impact of other chronic diseases, we compared the prevalence of poor HRQOL (the first quartile of EQ-VAS and EQ-5Dindex) based on vitamin D status after excluding participants comorbid chronic disease*. Vitamin D status were classified into two groups according to serum 25(OH)D concentration: Vitamin D normal (≥10 ng/mL) and deficiency (<10 ng/mL).
  2. *Participancts comorbid chronic disease included subjects with hypertension, diabetes, dyslipidaemia, cerebrovascular accident, chronic renal disease, or liver cirrhosis.
  3. †Statistically significant p-value ≤ 0.05. P-values were determined by multivariate logistic regression analysis.
  4. Model1: Adjusted for age & gender.
  5. Model2: Adjusted for age, gender + marital status, KL grade.
  6. Model3: Adjusted for age, gender + marital satus, KL grade + education, income, residence, smoking, regular exercise‡, BMI, WC.
  7. ‡Regular exercise was defined as participating in vigorous exercise (strenuous or gasping activities, such as running, high-speed cycling, and swimming) more than 3 times per week for ≥20 min at a time or moderate-intensity exercise (slightly strenuous or gasping activities, such as slow swimming, badminton, and table tennis) more than 5 times per week for ≥30 min at a time, or walking more than 5 times per week for ≥30 min at a time.
  8. Abbreviation: CI, confidence interval; BMI, body mass index; EQ-5D, EuroQOL-5 dimension; EQ-VAS, EuroQOL-visual analogue scale; HRQOL, health-related quality of life; KL grade, Kellgren-Lawrence grade; QOL, quality of life; Vit. D, vitamin D; WC, waist circumference.
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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