Table 2 Anchor-based approach for determining minimally important differences for the EQ-5D and SF-6D indices

EQ-5D index

  All

484

−0.04

(0.27)

0.003

0.15

0.07

442

−0.05

(0.26)

0.001

0.17

0.08

  Sizeable better

17

0.17

(0.26)

0.015

0.66

0.71

23

0.23

(0.31)

<0.001

0.76

0.72

  Minimally better

86

0.08*

(0.21)

<0.001

0.38

0.28

27

0.09*

(0.28)

0.048

0.32

0.31

  No change

220

−0.01

(0.22)

0.413

0.06

0.03

281

−0.01

(0.19)

0.471

0.06

0.03

  Minimally worse

115

−0.12*

(0.26)

<0.001

0.47

0.46

53

−0.12*

(0.23)

<0.001

0.50

0.43

  Sizeable worse

46

−0.27

(0.26)

<0.001

0.75

0.84

58

−0.33

(0.34)

<0.001

0.97

1.27

P-value^§

<0.001

<0.001

SF-6D index

  All

484

0.01

(0.14)

0.520

0.04

0.01

442

0.01

0.14

0.334

0.05

0.01

  Sizeable better

19

0.16

(0.13)

0.002

1.21

1.33

23

0.14

(0.12)

<0.001

1.17

1.40

  Minimally better

86

0.07*

(0.13)

<0.001

0.52

0.58

27

0.14*

(0.15)

<0.001

0.92

1.11

  No change

220

0.01

(0.13)

0.296

0.07

0.08

281

0.01

(0.14)

0.373

0.05

0.08

  Minimally worse

115

−0.04*

(0.12)

<0.001

0.33

0.36

53

−0.04*

(0.13)

0.068

0.27

0.33

  Sizeable worse

46

−0.08

(0.12)

<0.001

0.50

0.53

58

−0.06

(0.12)

<.0001

0.53

0.55

P-value^§

<0.001

<0.001