Table 4 Results of Step 3 from the ANCOVA investigating the relationship between sociodemographic factors and morbidity on patients’ health-related quality of life measured using the EQ-5D
Endpoint/Factors | EQ-5D Index | EQ-5D VAS | ||||
|---|---|---|---|---|---|---|
Baseline | Difference between week 54 and baseline | p value | Baseline | Difference between week 54 and baseline | p value | |
Age class | <0.0001 | |||||
<=60 years | 0.92 (0.12) | 0.00 (0.12) | ||||
>60 years | 0.89 (0.14) | 0.00 (0.13) | ||||
Gender | 0.0005 | 0.0002 | ||||
Male | 0.94 (0.11) | 0.00 (0.10) | 75.6 (14.2) | −8.50 (13.59) | ||
Female | 0.89 (0.15) | 0.00 (0.14) | 71.4 (15.4) | −9.30 (15.08) | ||
BMI | 0.0426 | |||||
<=25 kg/m2 | 0.94 (0.11) | 0.00 (0.12) | ||||
>25 to < =30 kg/m2 | 0.92 (0.13) | 0.00 (0.12) | ||||
= > 30 kg/m2 | 0.91 (0.13) | 0.00 (0.13) | ||||
Diabetes | 0.0101 | |||||
Yes | 69.2 (15.4) | −8.60 (15.91) | ||||
No | 74.1 (14.8) | −8.90 (14.14) | ||||
Cardiovascular disease | <0.0001 | |||||
Yes | 70.4 (14.5) | −10.90 (13.83) | ||||
No | 74.5 (15.5) | −8.10 (14.55) | ||||
Country (region) | 0.0085 | |||||
Western-central countries | 76.0 (15.5) | −7.80 (15.50) | ||||
Eastern countries | 72.0 (14.5) | −9.40 (13.81) | ||||
Concomitant medication for cardiovascular disease | 0.0065 | |||||
Yes | 0.91 (0.13) | 0.00 (0.12) | ||||
No | 0.92 (0.12) | 0.00 (0.13) | ||||
Concomitant medication for mental disorder | 0.021 | 0.0263 | ||||
Yes | 0.88 (0.17) | 0.00 (0.19) | 68.7 (17.8) | −10.40 (18.05) | ||
No | 0.92 (0.13) | 0.00 (0.12) | 73.6 (14.7) | −8.80 (14.22) | ||
Hypertension grade at baseline | 0.0258 | |||||
Grade 1 | 80.6 (11.8) | −1.10 (11.09) | ||||
Grade 2 | 73.4 (15.0) | −8.80 (14.25) | ||||
Grade 3 | 72.4 (15.2) | −10.40 (15.67) | ||||
Achieved hypertension control by week 54 | 0.0019 | |||||
Yes | 0.92 (0.13) | 0.00 (0.12) | ||||
No | 0.89 (0.15) | 0.00 (0.14) | ||||
Baseline value of respective endpoint | <0.0001 | <0.0001 | ||||
SeSBP changes from baseline to week 54 | 0.0010 | 0.0160 | ||||
SeDPB changes from baseline to week 54 | 0.0039 | 0.0120 | ||||