Table 2 Comparison between patients with decreased physical component summary and patients with unchanged or increased physical component summary at day 30 after surgery (univariate analysis)
Physical component summary | Decreased n=35 | Unchanged/increased n=50 | p Value | |
|---|---|---|---|---|
HRQoL | ||||
Preoperative physical component summary (PCS) | mean ± SD | 46.4 ± 9.8 | 33 ± 7.1 | < 0.001** |
Postoperative physical component summary (PCS) | mean ± SD | 32.9 ± 7.9 | 36.6 ± 7.5 | 0.034 |
Preoperative mental component summary (MCS) | mean ± SD | 41 ± 13 | 43.1 ± 12.8 | 0.461 |
Postoperative mental component summary (MCS) | mean ± SD | 42.5 ± 12.3 | 44.2 ± 12.6 | 0.538 |
Patient data | ||||
Female | n (%) | 19 (54.3) | 25 (50) | 0.826 |
Age | mean ± SD | 65.3 ± 10.7 | 67.6 ± 12.2 | 0.249 |
Weight | mean ± SD | 73.5 ± 16.1 | 73.5 ± 14.7 | 0.980 |
Preoperative assessments | ||||
Functional impairment | ||||
Independency of health care - independent | n (%) | 34 (97.1) | 41 (82) | 0.042 |
Karnofsky score | median (IQR) | 90 (90-90) | 80 (80-90) | 0.003 |
Exercise capacity | ||||
Metabolic equivalent of task (MET) >7 | n (%) | 10 (28.6) | 6 (12) | 0.0014** |
Metabolic equivalent of task (MET) 4-7 | n (%) | 24 (68.6) | 27 (54.0) | |
Metabolic equivalent of task (MET) <4 | n (%) | 1 (2.86) | 17 (34.0) | |
Severity of comorbidity | ||||
Charlson comorbidity index (adjusted for age) | median (IQR) | 1.5 (0-4) | 3 (0-5) | 0.372 |
ASA | median (IQR) | 2 (2-3) | 2 (2-3) | 0.997 |
Physiological part of POSSUM | median (IQR) | 16 (15-23) | 18.5 (15-23) | 0.778 |
Surgery | ||||
Primary hip replacement | n (%) | 12 (34.3) | 30 (60) | 0.038 |
Cardiac valve surgery | n (%) | 7(20) | 8 (16) | |
Gastric, esophageal or pancreatic surgery | n (%) | 3 (8.6) | 3 (6) | |
Colorectal surgery | n (%) | 12 (34.3) | 5 (10) | |
Femoropopliteal, femorotibial bypass | n (%) | 1 (2.9) | 4 (8) | |
Severity of surgery | ||||
Operative part of POSSUM | median (IQR) | 10 (9-13) | 10 (9-12) | 0.501 |
Major | n (%) | 25 (71) | 39 (78) | 0.489 |
Major + | n (%) | 10 (29) | 11 (22) | |
Anesthesia | ||||
General anesthesia | n (%) | 25 (71.4) | 37 (74) | 0.165 |
Epidural/Spinal anesthesia | n (%) | 1 (2.9) | 6 (12) | |
Combined anesthesia | n (%) | 9 (25.7) | 7 (14) | |
Timing | ||||
Time from admission to surgery (h) | mean ± SD | 106.6 ± 290.3 | 44.2 ± 57.2 | 0.283 |
Time from admission to surgery; >24h | n (%) | 11 (31.4) | 9 (18) | 0.058 |
Surgery duration (h) | mean ± SD | 3.0 ± 1.8 | 2.4 ± 0.8 | 0.242 |
Anesthesia duration (h) | mean ± SD | 4.3 ± 2.0 | 3.7 ± 1.0 | 0.330 |
Intraoperative complications | n (%) | 21 (60) | 30 (60) | 1 |
Postoperative complications (Clavien ≥ 2) | ||||
Day 2* | n (%) [n] | 14 (40) [34] | 18 (36) [50] | 0.654 |
Day 7* | n (%) [n] | 18 (51) [30] | 19 (38) [41] | 0.337 |
Postoperative comfort | ||||
Pain at the surgical site - Numerical rating scale (NRS) | ||||
Day 1* | median (IQR) [n] | 5 (2-7) [27] | 5 (3-7) [45] | 0.367 |
Day 6* | median (IQR) [n] | 3 (0-5) [28] | 4 (2-5) [40] | 0.074 |
Pain, other - Numerical rating scale (NRS) | ||||
Day 1* | median (IQR) [n] | 0 (0-5) [27] | 0 (0-5) [45] | 0.738 |
Day 6* | median (IQR) [n] | 0.5 (0-5) [28] | 0 (0-4) [40] | 0.509 |
Comfort Estimation - Numerical rating scale (NRS) | ||||
Day 1* | median (IQR) [n] | 6 (5-8) [27] | 6 (5-8) [44] | 0.910 |
Day 6* | median (IQR) [n] | 7 (5-8.5) [27] | 8 (5.8-8) [40] | 0.481 |
Clinical itinerary | ||||
Simple | n (%) | 31 (88.6) | 43 (86.0) | 1.000 |
Complex | n (%) | 4 (11.4) | 7 (14.0) | |
Hospital stay - days | median (IQR) | 14 (9-19) | 12 (9-14.8) | 0.580 |