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Table 3 Evaluation of the SCD-MHC as an indicator of SCD severity

From: Patient reports of health outcome for adults living with sickle cell disease: development and testing of the ASCQ-Me item banks

Evaluation variables F-Stat
  SCD-MHC ǂ Non-SCD-MHC ¥
What is your age? 47.07*** 00.17
Past 12 mos, how many times did you go to the ED because of a pain attack (crisis)? 12.03*** 03.00
Severity of Vaso-Occlusive Events 04.3* 00.80
Past 12 mos, how many sickle cell pain attacks (crises) did you have? 03.57 06.35**
When was your last pain attack (crisis)? 05.96* 00.27
Rate severity of pain in last attack 12.54*** 00.03
How much did your last pain attack (crisis) interfere with your life? 13.24*** 00.03
About how long did your most recent pain attack (crisis) last? 36.37*** 03.10
PROMIS Globals 31.99*** 02.29
In general, would you say your health is: 32.13*** 02.29
In general, would you say your quality of life is: 10.22** 07.36**
In general, how would you rate your physical health? 10.64*** 06.64**
In general, how would you rate your mental health, including your mood and your ability to think? 27.79*** 18.82***
…, how would you rate your satisfaction with your social activities and relationships? 31.91*** 07.80**
To what extent are you able to carry out your everyday physical activities? 6.59** 04.56*
Past 7 days, how would you rate your pain on average? 31.63*** 00.61
Past 7 days, how would you rate your fatigue on average? 03.07 10.13**
Past 7 days, please rate how well you carry out your usual social activities and roles 47.07*** 00.17
Past 7 days, how often … bothered by emotional problems such as…? 12.03*** 03.00
  1. ǂSCD-MHC = Sickle Cell Disease Medical History Checklist.
  2. ¥Non-SCD-MHC = Checklist of medical history conditions not associated with Sickle Cell Disease.