The psychometric properties of the St George’s Respiratory Questionnaire (SGRQ) in patients with idiopathic pulmonary fibrosis: a literature review

Table 6 Changes in SGRQ scores in within-subject clinical trials

Study	Treatment under investigation	Treatment duration	Sample size		SGRQ total score¹		Effect size	p-value²
Study	Treatment under investigation	Treatment duration	Total	IPF	Baseline	Post-treatment	Effect size	p-value²
Mishra et al., 2011 [22]	Oral doxycycline	24 weeks	6	6	50.90 (8.38)	18.40 (6.39)	3.88	<0.001
Naji et al., 2006 [23]	Pulmonary rehabilitation	8 weeks	26	19	48.3 [21.5, 82]	39.5 [17.4, 69.4]	0.41	<0.10
Rammaert et al., 2009 [32]	Pulmonary rehabilitation	8 weeks	13	13	–	–	–	NS
Tzouvelekis et al., 2013 [37]	Endobronchial infusion of adipose-derived stromal cells	6 months	14	14	35.1 (6.8)	27.8 (5.6)	1.07	<0.05

¹Mean (SD) or median [range] are reported based on availability.
²p-value for test of statistical significance between SGRQ score at baseline and post-treatment.

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